 |
dadamowiki A wikipedia of Dr. D'Adamo's research |
Soyasaponins
C O N T E N T S
- See Also
- Description
- Discussion
- Abstracts
- Soyasaponin I, a potent and specific sialyltransferase inhibitor
- Human fecal metabolism of soyasaponin I
- Soyasaponin-I-modified invasive behavior of cancer by changing cell surface sialic acids
- Soyasaponin I decreases the expression of alpha2,3-linked sialic acid on the cell surface and suppresses the metastatic potential of B16F10 melanoma cells
- References
See Also- Saponins
- Sialic acid and sialyltransferase dysfunction in breast cancer
- Sialic acid
- Glycosyltransferase
- Thomsen-Friedenreich (T-Tn) antigen
Description
Soyasaponins are bioactive compounds found in many legumes. Results from in vitro fermentation suggested that colonic microflora readily hydrolyzed the soyasaponins to aglycones .
Discussion
Soyasaponins appear to be significant inhibitors of sialyltransferase , which may indicate a significant role in cancer chemotherapeutics and prevention.
These observations suggest that the soyasaponins may be an important dietary chemopreventive agent against colon cancer, after alteration by microflora.( {{Gurfinkel DM, Rao AV. Soyasaponins: the relationship between chemical structure and colon anticarcinogenic activity.
|
The statements made on our websites have not been evaluated by the FDA (U.S. Food & Drug Administration).
Our products and services are not intended to diagnose, cure or prevent any disease. If a condition persists, please contact your physician.
Copyright © 2015-2026, Hoop-A-Joop, LLC, Inc. All Rights Reserved.