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Haplogroup V (mtDNA)

Archaeogenetics

See Also

• Haplogroup HV (mtDNA)
• Haplogroups
• Haplotype
• Mitochondrial DNA
• Mitochrondrial DNA Haplogroups
• Mitochondrial genetics
• Paleolithic
• Rhesus (Rh) Blood Group

Description

Haplogroup V is a human mitochondrial DNA (mtDNA) haplogroup.

Haplogroup V is believed to have originated approximately 12,000 years before present, possibly in Iberia. It is found with particularly high concentrations in the Saami population of northern Scandinavia, as well as the Basque people.

Source

Haplogroup V derives from the  Haplogroup HV, which also gave rise to  Haplogroup H.

In his popular book The Seven Daughters of Eve, Bryan Sykes named the originator of this mtDNA haplogroup Velda.

Links

• Spread of Haplogroup V, from National Geographic
• Velda

Abstracts

An mtDNA analysis in ancient Basque populations: implications for haplogroup V as a marker for a major paleolithic expansion from southwestern europe

Am J Hum Genet. 1999 Jul;65(1):199-207. Izagirre N, de la Rua C.

• mtDNA sequence variation was studied in 121 dental samples from four Basque prehistoric sites, by high-resolution RFLP analysis. The results of this study are corroborated by (1) parallel analysis of 92 bone samples, (2) the use of controls during extraction and amplification, and (3) typing by both positive and negative restriction of the linked sites that characterize each haplogroup. The absence of haplogroup V in the prehistoric samples analyzed conflicts with the hypothesis proposed by Torroni et al., in which haplogroup V is considered as an mtDNA marker for a major Paleolithic population expansion from southwestern Europe, occurring approximately 10,000-15,000 years before the present (YBP). Our samples from the Basque Country provide a valuable tool for checking the previous hypothesis, which is based on genetic data from present-day populations. In light of the available data, the most realistic scenario to explain the origin and distribution of haplogroup V suggests that the mutation defining that haplogroup (4577 NlaIII) appeared at a time when the effective population size was small enough to allow genetic drift to act-and that such drift is responsible for the heterogeneity observed in Basques, with regard to the frequency of haplogroup V (0%-20%). This is compatible with the attributed date for the origin of that mutation (10,000-15, 000 YBP), because during the postglacial period (the Mesolithic, approximately 11,000 YBP) there was a major demographic change in the Basque Country, which minimized the effect of genetic drift. This interpretation does not rely on migratory movements to explain the distribution of haplogroup V in present-day Indo-European populations.

Attribution

• This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Haplogroup V (mtDNA)".

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