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'A-Like' tumor antigens
[[Pathology]] ====See Also==== * [[Aberrent glycosylation in malignant and pre-malignant states]] * [[Forssman . . . JMH, Hy/Gy, Do and Emm BGAs. The most important ligand for P, E and L selectins is sialyl-Le(x). This . . .
16K - last updated 2006-06-30 17:45 UTC by PeterDAdamo
Carbohydrate antigens sialyl Lewis A and sialyl Lewis X and adhesion of human cancer cells to vascular endothelium
[[References]] ====Carbohydrate antigens sialyl Lewis A and sialyl Lewis X and adhesion of human cancer . . . antigen, sialyl Lex, is known to be a ligand for the cell adhesion molecule called ELAM-1 . . . antigen, sialyl Lea, can also serve as a ligand for ELAM-1 (A. Takada, K. Ohmori, N. Takahashi, . . .
3K - last updated 2006-05-04 22:42 UTC by PeterDAdamo
[[Biochemistry]] ====See Also==== In chemistry, a dimer refers to a molecule composed of two similar . . . (usually through a kinase protein), or a ligand. An example of this dimerizing activity involves . . .
3K - last updated 2006-05-05 10:51 UTC by PeterDAdamo
Duffy blood group system
[[Polymorphism]] ====See Also==== * [[Allele]] * [[Chemokines]] * [[Interleukin-8 (IL-8)]] FY Gene locus . . . cells, DARC is internalized following ligand binding and this led to the hypothesis that . . . efficiently internalize their cognate chemokine ligands, thus act as "interceptors" (internalizing . . .
15K - last updated 2006-05-14 19:52 UTC by PeterDAdamo
[[Nutrigenomics]] ====See Also==== * [[FUT1]] * [[FUT2]] * [[FUT4]] * [[19q13.3]] * [[Lewis antigens]] . . . saliva could be explained by an optimal H type 1 ligand density, which was lower than that in blood . . . blood group B saliva. Indeed, despite a higher ligand density, saliva from homozygotes with 2 functional . . . that optimal attachment occurred at medium ligand density. ====Links==== * [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=full_report&list_uids=2525 . . .
6K - last updated 2006-05-06 12:06 UTC by PeterDAdamo
[[Biochemistry]] ====See Also==== * [[Ligand]] * [[Receptor]] * [[Receptor antagonist]] * [[Second messengers]] . . . that transduce an extracellular signal (ligand binding) into an intracellular signal (G protein . . . of functions is matched by the wide range of ligands recognized by members of the family, from photons . . . and inflammation: chemokine receptors bind ligands that mediate intercellular communication between . . . entire ion channels, within their protein. ====Ligand binding and signal transduction==== http://www.dadamo.com/wiki/7m.jpg . . .
10K - last updated 2006-07-08 10:41 UTC by PeterDAdamo
H-h blood group system
[[Polymorphism]] ====See Also==== * [[Allele]] * [[Antigen]] * [[Blood group antigen proteins (chart)]] . . . are the products of FUT1 and FUT2 may serve as ligands in cell adhesion or as receptors for certain . . .
12K - last updated 2006-08-06 20:50 UTC by TomGreenfield
[[Serology]] ====See also=== * [[Allergy]] * [[Allergy, ABO Blood Group and Secretor Status]] * [[Allergens, . . . A, a sialoglycoprotein that represents a major ligand for several bacteria and viruses that recognize . . .
6K - last updated 2006-05-12 09:24 UTC by PeterDAdamo
[[Biochemistry]] ====See Also==== * [[Agonist]] * [[G-protein-coupled receptors]] * [[Receptor]] * [[Receptor . . . ====Description==== In biochemistry, a <b>ligand</b> is an effector, a molecule that binds . . . Actual coordinate covalent bonds between a ligand and its target molecule are rare in biological . . . systems. Ligands include substrates, inhibitors, activators, . . . and neurotransmitters. Whether or not the ligand actually binds at a metal site is irrelevant, . . .
5K - last updated 2006-07-08 10:37 UTC by PeterDAdamo
[[Glycomics]] ====See Also==== * [[Mucin]] * [[Aberrent glycosylation in malignant and pre-malignant . . . (EGFR) in lactating glands1. Muc1 can act as a ligand for ICAM-1 on HUVEC cells; it can bind β-catenin, . . .
4K - last updated 2006-05-03 22:50 UTC by PeterDAdamo
[[Biochemistry]] ====See Also==== * [[G-protein-coupled receptors]] * [[Ligand]] * [[Receptor antagonist]] . . . nucleus that binds to a specific molecule (a ligand), such as a neurotransmitter, hormone, or other . . . and initiates the cellular response to the ligand. Ligand-induced changes in the behavior of receptor . . . that constitute the biological actions of the ligands. http://www.dadamo.com/wiki/recept.jpg Transmembrane . . . exist in different types, dependant on their ligand and function: * Some receptor proteins are peripheral . . .
5K - last updated 2006-07-08 10:37 UTC by PeterDAdamo
Sialic acid and sialyltransferase dysfunction in breast cancer
[[Pathology]] ====See Also==== * [[Glycomics]] * [[Soyasaponins]] * [[Sialotransferases]] ====Discussion==== . . . endothelial molecule E-selectin and its tumoral ligands sialyl-Lewis- and sialyl-Lewis. Sialyltranferases . . . are involved in the biosynthesis of these ligands. The aim of this study was to assess the prognostic . . .
2K - last updated 2006-05-01 21:35 UTC by PeterDAdamo
Sialyl Lewis X (SLeX)
[[Polymorphism]] ====See Also==== * [[Carbohydrate]] * [[Carbohydrates as Biological Markers]] * [[Cell . . . interactions between lectins and oligosaccharide ligands. http://www.dadamo.com/wiki/selx.jpg However . . .
2K - last updated 2006-05-06 12:03 UTC by PeterDAdamo
[[Lectinology]] ====See Also==== * [[19q13.3]] * [[Carbohydrates as Biological Markers]] * [[Cell Adhesion . . . residues such as GD3 and GD1b. Thus, potential ligands for sialoadhesin are likely to be found on . . .
9K - last updated 2006-05-06 10:14 UTC by PeterDAdamo
[[Physiology]] ====See Also==== * [[Nitric Oxide]] * [[Proteasome]] * [[Second messengers]] ====Description==== . . . respond only to the specific molecule or ligand for which they have affinity, and molecules . . . nutrient. In complex organisms this includes the ligands responsible for sensations of smell and taste. . . . receptors that are ion channels===== A ligand-activated ion channel will recognize its ligand, . . . the signal cascade. The nuclear receptors are ligand-activated transcription activators; on binding . . .
21K - last updated 2006-07-07 11:58 UTC by PeterDAdamo
[[Glycomics]] ===See Also==== * [[Glycoproteins]] ====Description==== Thrombospondins (TSP) are secreted . . . bind to CD36, leading to the expression of FAS ligand (FasL), which activates the expression of Fas. . . .
2K - last updated 2006-04-25 20:12 UTC by PeterDAdamo
Toll-like receptors (TLRs)
[[Immunology]] ====See Also==== * [[Interleukin-1 (IL-1)]] * [[Interleukin-6 (IL-6)]] * [[Interleukin-8 . . . TLR1 or TLR6, each dimer having a different [[ligand]] specificity. TLRs may also depend on other . . . co-receptors for full ligand sensitivity, such as in the case of TLR4's recognition . . . </td><td> Ligand PAMP(s) </td><td> Activation Cascade(s)</td></tr> . . .
8K - last updated 2006-05-23 07:33 UTC by AlanGoldenberg
<table><tr><td> http://www.dadamo.com/wiki/coral-sm.jpg </td><td>Articles . . . antagonist" "G-protein-coupled receptors" "Ligand" "Receptor" "Signal transduction" "Proteasome" . . .
2K - last updated 2007-08-20 01:47 UTC by AlanGoldenberg
18 pages found.