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Bauhinia purpurea : Camels's foot tree
BPA
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Molecular structure of
Camels's foot tree:BPA
|
Bauhinia purpurea
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| Lecster ID:79 | Edit Entry |
| Source Organism: | Camels's foot tree |
| Species: | Bauhinia purpurea |
| Common Nomenclature: | BPA |
| Class: | Legume lectin |
| Index Nomenclature: | LECp.Bau.Pur.se.Hga1 |
| Characterization Notes: | Siliar lectins were found in Bauhinia violacea and other Bauhinia species. |
| Biological Activity: | BPA agglutinates blood group N. See: Annal NY Acad. Sci. 1970 (169) 168-90 It appears to agglutinates all human erythrocytes. See: Archiv. Biochem. Biophysic. 1972 (151) 475-482 The lectin binds to normal and cancerous thyroid tissue. See: Pathologica; Research and Practice 1994 (190); 105-1011 BPA inhibits Herpes simplex virus and rabies virus in vitro. See: Res. Virol. 1995 (146); 211-215 The lectin is a useful tool for the detection of galactose containing glycoconjugates and is used as a marker for Reed-Sternberg cells of Hodgkin's Disease. See: Amer. J. Pathol. 1992 (141); 19-23 The binding property of a cyst glycoprotein from a human blood group Le(a+) nonsecretor individual, that contains an unusually high amount (18%) of sialic acid was characterized by quantitative precipitin assay with a panel of lectins including BPA, which had a 37% rate of precipitation. See: Biochim Biophys Acta 1996 Jun 7;1316(2):139-44 |
| Source Tissue: | Seeds |
| Specificity: | GalNAc(Gal beta(1,3)GalNAc (T-antigen)>GalNAc>Gal |
| Inhibitors: | |
| References: | FEBS Lett 1991 Apr 9;281(1-2):258-62 |
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