For characterization of Iscador, a mistletoe preparation with alleged cancerostatic properties, see: Oncology 1988;45(3):172-9 Apparently, viscumin consists of two chains which, in some of the molecules, are disulfide-linked. The A chain was found to inhibit protein synthesis by inactivating the ribosomes catalytically. See: J Biol Chem 1982 Nov 25;257(22):13263-70
Biological Activity:
Source Tissue:
Specificity:
Terminal beta-Gal residues
Inhibitors:
Lactose
References:
J. Biol. Chem. (1975) 250, 8518, J. Immunol (1978) 121, 438 Biochim Biophys Acta. 1990 Jun 20;1034(3):247-52.