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LECSTER is the largest, open-access searchable database of lectin characterizations, clinical correlates and citations on the Internet.

Programmed and curated by Peter D'Adamo.

Copyright 2001-2011.

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Total number of records: 619 Matching records: 1

Trichosanthes japonica : Serpent cucumber

Molecular structure of
Serpent cucumber:TJA-II, TJA-I, TK-I, TK-II

Trichosanthes japonica

Lecster ID:626 Edit Entry
Source Organism:Serpent cucumber
Species:Trichosanthes japonica
Common Nomenclature:TJA-II, TJA-I, TK-I, TK-II
Index Nomenclature:LECp.Tri.Jap.xx.Xxxx
Characterization Notes:A series of oligosaccharides possessing Fuc alpha 1-->2Gal beta 1--> or GalNAc beta 1--> groups at their nonreducing terminals showed stronger binding ability than ones with Gal beta 1-->GlcNAc (Glc) groups. For partial characterization of a lectin from the seeds of Trichosanthes kirilowii Maximowicz, see: FEBS Lett 1989 Mar 27;246(1-2):159-62 For characterization of lectin from Trichosanthes kirilowii root tubers, see: Int J Pept Protein Res 1986 Feb;27(2):208-20
Biological Activity:
Source Tissue:
Specificity:Fuc alpha 1-->2Gal beta/GalNAc beta 1-->groups. TJA-I basically recognizes an N-acetyllactosamine residue and that the binding strength increases on substitution of the beta-galactosyl residue at the C-6 position with a sialic acid or sulfate.
References:Biochemistry. 1992 Nov 24;31(46):11647-50.

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By Peter D'Adamo. Copyright 2001-2011.