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Trichosanthes japonica : Serpent cucumber
TJA-II, TJA-I, TK-I, TK-II
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Molecular structure of
Serpent cucumber:TJA-II, TJA-I, TK-I, TK-II
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Trichosanthes japonica
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| Lecster ID:626 | Edit Entry |
| Source Organism: | Serpent cucumber |
| Species: | Trichosanthes japonica |
| Common Nomenclature: | TJA-II, TJA-I, TK-I, TK-II |
| Class: | |
| Index Nomenclature: | LECp.Tri.Jap.xx.Xxxx |
| Characterization Notes: | A series of oligosaccharides possessing Fuc alpha 1-->2Gal beta 1--> or GalNAc beta 1--> groups at their nonreducing terminals showed stronger binding ability than ones with Gal beta 1-->GlcNAc (Glc) groups. For partial characterization of a lectin from the seeds of Trichosanthes kirilowii Maximowicz, see: FEBS Lett 1989 Mar 27;246(1-2):159-62 For characterization of lectin from Trichosanthes kirilowii root tubers, see: Int J Pept Protein Res 1986 Feb;27(2):208-20 |
| Biological Activity: | |
| Source Tissue: | |
| Specificity: | Fuc alpha 1-->2Gal beta/GalNAc beta 1-->groups. TJA-I basically recognizes an N-acetyllactosamine residue and that the binding strength increases on substitution of the beta-galactosyl residue at the C-6 position with a sialic acid or sulfate. |
| Inhibitors: | |
| References: | Biochemistry. 1992 Nov 24;31(46):11647-50. |
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