For isolation, characterization, and interaction with type A blood-group substance, see: Biochemistry. 1972 Oct 10;11(21):3976-84
Biological Activity:
Blood group A; at agglutination titer of 1:128 by crude lectin preparation (16mg/ml). See: Int J Cancer 1970;6:283 The lima bean lectin exhibits blood group specificity towards human type A erythrocytes. See: FEBS Letters 1970 (9); 197-201 The lima bean lectin is mitogenic for T- but not B-lymphocytes. The lectin LBL, is much more active than the lectin LBL4 as a mitogen for normal lymphocytes. The lectin LBL, also stimulates mitogenesis in leukaernic lymphocytes whereas LBL4 has minimal activity on these cells. See: Proc Nat Acad Sci 1974 (71); 1848-1851 Oral administration of the lima bean lectin to rats severely retarded the growth of the animals. See: Toxicon 1972 (10);89-91
Source Tissue:
Seeds
Specificity:
GalNAc(GalNAc alpha(1,3)[Fuc alpha(1,2)] Gal>alpha-GalNAc>alpha-Gal; Blood group A)
Inhibitors:
References:
2013-5-18: Current Date 12:51:42 GMT: Current Time
