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|Phaseolus limenesis : Lima bean|
PLA, LBA, LBL
Molecular structure of
Lima bean:PLA, LBA, LBL
|Lecster ID:509|| Edit Entry |
|Source Organism:||Lima bean|
| Common Nomenclature:||PLA, LBA, LBL|
|Characterization Notes:||For isolation, characterization, and interaction with type A blood-group substance, see: Biochemistry. 1972 Oct 10;11(21):3976-84|
|Biological Activity:||Blood group A; at agglutination titer of 1:128 by crude lectin preparation (16mg/ml). See: Int J Cancer 1970;6:283 The lima bean lectin exhibits blood group specificity towards human type A erythrocytes. See: FEBS Letters 1970 (9); 197-201 The lima bean lectin is mitogenic for T- but not B-lymphocytes. The lectin LBL, is much more active than the lectin LBL4 as a mitogen for normal lymphocytes. The lectin LBL, also stimulates mitogenesis in leukaernic lymphocytes whereas LBL4 has minimal activity on these cells. See: Proc Nat Acad Sci 1974 (71); 1848-1851 Oral administration of the lima bean lectin to rats severely retarded the growth of the animals. See: Toxicon 1972 (10);89-91|
|Specificity:||GalNAc(GalNAc alpha(1,3)[Fuc alpha(1,2)] Gal>alpha-GalNAc>alpha-Gal; Blood group A)|
2015-2-27: Current Date 22:45:24 GMT: Current Time
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