LECSTER LECTIN DATABASE









LECSTER is the largest, open-access searchable database of lectin characterizations, clinical correlates and citations on the Internet.


Programmed and curated by Peter D'Adamo.

Copyright 2001-2011.



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Total number of records: 619 Matching records: 1

Oncorhynchus mykiss : Steelhead trout
Ladderlectin



Molecular structure of
Steelhead trout:Ladderlectin
Oncorhynchus mykiss


Lecster ID:469 Edit Entry
Source Organism:Steelhead trout
Species:Oncorhynchus mykiss
Common Nomenclature:Ladderlectin
Class:
Index Nomenclature:LECa.Onc.Myk.xx.Xxxx
Characterization Notes:The lectin appears as a characteristic ladder of bands with approximately 16 kDa between consecutive bands. Upon reduction, the lectin appears as a 16-kDa band. Sequence alignment and phylogenetic analysis of the carbohydrate -recognition domain indicate that the protein has similarity with human dendritic cell immunoreceptor (DCIR), gp120 binding C-type lectin (gp120BCL) and mammalian hepatic lectins.
Biological Activity:
Source Tissue:
Specificity:
Inhibitors:Glucose, N-acetyl-glucosamine, mannose, N-acetyl-mannosamine, L-fucose, maltose and alpha-methyl-mannoside are good inhibitors of this binding, whereas glucosamine and D-fucose inhibits to a lesser degree and mannosamine and galactose do not inhibit
References:Biochim Biophys Acta 2000 Nov 15;1494(1-2):14-22




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2013-5-25: Current Date 2:45:8 GMT: Current Time

By Peter D'Adamo. Copyright 2001-2011.