Amaranthin is a highly specific tool probe for the T and cryptic T antigens. See: J. Biolog. Chem. 1989 (264); 16 123-16 131 Amaranthin is used as a histochemical probe for proliferating cells in human colonic tissue. See Biochemistry 1992 (31); 4308-4313 Amaranthin represents about 3.7% of the PBS extractable protein in seed meal. See: See: J. Biolog. Chem. 1989 (264); 16 123-16 131 A lectin with similar T-antigen binding specificity is present in Artocarpus integrifolia seeds.
Biological Activity:
The Amaranthus lectin agglutinates human ABO and sheep, goat, rat rabbit and guinea pig erythrocytes. See: Plant Sci. 1993 (94); 47-53
Source Tissue:
Specificity:
Chitin binding protein, GalNAc (T-antigen disaccharide and its alpha-linked glycosides (Galß(1,3)GalNAc-alpha-O-R)
Inhibitors:
References:
J. Mol. Biol., 258, 322-333, 1996 J. Biolog. Chem. 1989 (264); 16 123-16 131
