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LECSTER is the largest, open-access searchable database of lectin characterizations, clinical correlates and citations on the Internet.

Programmed and curated by Peter D'Adamo.

Copyright 2001-2011.

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Total number of records: 619 Matching records: 1

Aloe arborescens : Narrow-leaved sword aloe
Aloctin, AAA

Molecular structure of
Narrow-leaved sword aloe:Aloctin, AAA

Aloe arborescens

Lecster ID:45 Edit Entry
Source Organism:Narrow-leaved sword aloe
Species:Aloe arborescens
Common Nomenclature:Aloctin, AAA
Class:AAA: Monocot mannose-binding proteins Aloctin-A: u
Index Nomenclature:LECp.Alo.Arb.le.? (Aloctin-A) LECp.Alo.Arb.le.Hma1 (AAA)
Characterization Notes:Aloctin A forms a precipitate with alpha 2 macroglobulin and activates complement C3. See:Phytotherapy Res. 1993 (7): S14-S19. Aloctin A shows anti-tumor activity, exhibits anti-inflammatory effects and inhibits gastric secretions and gastric lesions. See: Phytotherapy Res. 1993 (7): S14-S19.
Biological Activity:Has two lectins, S-1 (Aloctin-A) and P-2. S-1 has a strong hemagglutinating activity. On the other hand, P-2 (AAA) has not only hemagglutinating activity but also mitogenicactivity on lymphocytes, precipitate-forming reactivity with serum proteins, one of which is alpha2-macroglobulin, and complement C3 activating activity via the alternate pathway. See: J Biochem (Tokyo) 1979 Jan;85(1):163-71 Aloctin-A agglutinates human erythrocytes. See: Phytotherapy Res. 1993 (7): S14-S19. AAA is a potent mitogen for mouse lymphocytes. See: J. Biochem 1995 (118) 1205-1210
Source Tissue:
Specificity:AAA: mannose Aloctin-A: unknown

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2015-2-28: Current Date 21:11:17 GMT: Current Time

By Peter D'Adamo. Copyright 2001-2011.