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|Aloe arborescens : Narrow-leaved sword aloe|
Molecular structure of
Narrow-leaved sword aloe:Aloctin, AAA
|Lecster ID:45|| Edit Entry |
|Source Organism:||Narrow-leaved sword aloe|
| Common Nomenclature:||Aloctin, AAA|
|Class:||AAA: Monocot mannose-binding proteins Aloctin-A: u|
|Index Nomenclature:||LECp.Alo.Arb.le.? (Aloctin-A) LECp.Alo.Arb.le.Hma1 (AAA)|
|Characterization Notes:||Aloctin A forms a precipitate with alpha 2 macroglobulin and activates complement C3. See:Phytotherapy Res. 1993 (7): S14-S19. Aloctin A shows anti-tumor activity, exhibits anti-inflammatory effects and inhibits gastric secretions and gastric lesions. See: Phytotherapy Res. 1993 (7): S14-S19.|
|Biological Activity:||Has two lectins, S-1 (Aloctin-A) and P-2. S-1 has a strong hemagglutinating activity. On the other hand, P-2 (AAA) has not only hemagglutinating activity but also mitogenicactivity on lymphocytes, precipitate-forming reactivity with serum proteins, one of which is alpha2-macroglobulin, and complement C3 activating activity via the alternate pathway. See: J Biochem (Tokyo) 1979 Jan;85(1):163-71 Aloctin-A agglutinates human erythrocytes. See: Phytotherapy Res. 1993 (7): S14-S19. AAA is a potent mitogen for mouse lymphocytes. See: J. Biochem 1995 (118) 1205-1210|
|Specificity:||AAA: mannose Aloctin-A: unknown|
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