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|Machaerocereus eruca : Cactus|
Molecular structure of
|Lecster ID:421|| Edit Entry |
| Common Nomenclature:||MEA-I, MEA-II|
|Characterization Notes:||Four isolectins (ME-C2, -D2, E2, F2) have been isolated from M. eruca. Lectin activity has also been reported in other cacti, including: Pachydereus pringleii, Cholla opuntia, Echinocereus engelmanii, Lopocereus shotti, Stenocereus thurberi and Machaerocereus gummosus. See: Lectin: Biol Biochem Clin Biochem 1985 (4); 437-445|
|Biological Activity:||Both lectins agglutinate erythrocytes from several animal species. The lectin agglutinates all human erythrocytes. See: Plant Sci 1991 (77); 11-19 The lectin induces the inhibition of the phagocytic activity of murine macrophages. See: Glycoconj J 1995 (12); 699-706|
|Specificity:||Gal (GalNAc and Gal-containing glycoproteins ; O-glycans) Binding specificity was directed to galactose-containing oligosaccharides and glycopeptides.|
|Inhibitors:||Hapten inhintion assays were specific for galactose, N-acteylgalactosamine and galactose-containg glycoproteins|
|References:||FEBS Lett 1988 Sep 26;238(1):95-100|
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