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LECSTER is the largest, open-access searchable database of lectin characterizations, clinical correlates and citations on the Internet.

Programmed and curated by Peter D'Adamo.

Copyright 2001-2011.

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Total number of records: 619 Matching records: 1

Machaerocereus eruca : Cactus

Molecular structure of
Cactus:MEA-I, MEA-II

Machaerocereus eruca

Lecster ID:421 Edit Entry
Source Organism:Cactus
Species:Machaerocereus eruca
Common Nomenclature:MEA-I, MEA-II
Characterization Notes:Four isolectins (ME-C2, -D2, E2, F2) have been isolated from M. eruca. Lectin activity has also been reported in other cacti, including: Pachydereus pringleii, Cholla opuntia, Echinocereus engelmanii, Lopocereus shotti, Stenocereus thurberi and Machaerocereus gummosus. See: Lectin: Biol Biochem Clin Biochem 1985 (4); 437-445
Biological Activity:Both lectins agglutinate erythrocytes from several animal species. The lectin agglutinates all human erythrocytes. See: Plant Sci 1991 (77); 11-19 The lectin induces the inhibition of the phagocytic activity of murine macrophages. See: Glycoconj J 1995 (12); 699-706
Source Tissue:Stems
Specificity:Gal (GalNAc and Gal-containing glycoproteins ; O-glycans) Binding specificity was directed to galactose-containing oligosaccharides and glycopeptides.
Inhibitors:Hapten inhintion assays were specific for galactose, N-acteylgalactosamine and galactose-containg glycoproteins
References:FEBS Lett 1988 Sep 26;238(1):95-100

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By Peter D'Adamo. Copyright 2001-2011.