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Machaerocereus eruca : Cactus
MEA-I, MEA-II
|
Molecular structure of
Cactus:MEA-I, MEA-II
|
Machaerocereus eruca
|
| Lecster ID:421 | Edit Entry |
| Source Organism: | Cactus |
| Species: | Machaerocereus eruca |
| Common Nomenclature: | MEA-I, MEA-II |
| Class: | ? |
| Index Nomenclature: | LECp.Mac.Eru.st.Hga1 |
| Characterization Notes: | Four isolectins (ME-C2, -D2, E2, F2) have been isolated from M. eruca. Lectin activity has also been reported in other cacti, including: Pachydereus pringleii, Cholla opuntia, Echinocereus engelmanii, Lopocereus shotti, Stenocereus thurberi and Machaerocereus gummosus. See: Lectin: Biol Biochem Clin Biochem 1985 (4); 437-445 |
| Biological Activity: | Both lectins agglutinate erythrocytes from several animal species. The lectin agglutinates all human erythrocytes. See: Plant Sci 1991 (77); 11-19 The lectin induces the inhibition of the phagocytic activity of murine macrophages. See: Glycoconj J 1995 (12); 699-706 |
| Source Tissue: | Stems |
| Specificity: | Gal (GalNAc and Gal-containing glycoproteins ; O-glycans) Binding specificity was directed to galactose-containing oligosaccharides and glycopeptides. |
| Inhibitors: | Hapten inhintion assays were specific for galactose, N-acteylgalactosamine and galactose-containg glycoproteins |
| References: | FEBS Lett 1988 Sep 26;238(1):95-100 |
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