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LECSTER is the largest, open-access searchable database of lectin characterizations, clinical correlates and citations on the Internet.

Programmed and curated by Peter D'Adamo.

Copyright 2001-2011.

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Total number of records: 619 Matching records: 1

Homo sapiens :
Endothelial Cell-Selective Adhesion Molecule (ESAM)

Molecular structure of
:Endothelial Cell-Selective Adhesion Molecule (ESAM)

Homo sapiens

Lecster ID:364 Edit Entry
Source Organism:
Species:Homo sapiens
Common Nomenclature:Endothelial Cell-Selective Adhesion Molecule (ESAM)
Index Nomenclature:CDHh.Hom.Sapxxx
Characterization Notes:ESAM is a new member of the immunoglobulin superfamily. ESAM is selectively expressed in cultured human and murine vascular endothelial cells and revealed high level expression in lung and heart and low level expression in kidney and skin. In situ hybridization analysis indicated that ESAM is primarily expressed in the developing vasculature of the embryo in an endothelial cell-restricted pattern. Epitope-tagged ESAM was shown to co-localize with cadherins and catenins in cell-cell junctions.
Biological Activity:The endothelial cell-selective expression of this immunoglobulin-like adhesion molecule coupled with its in vitro functional profile strongly suggests a role in cell-cell interactions that is critical for vascular development or function.
Source Tissue:
References:J Biol Chem 2001 May 11;276(19):16223-31

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2015-2-28: Current Date 19:23:51 GMT: Current Time

By Peter D'Adamo. Copyright 2001-2011.