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LECSTER is the largest, open-access searchable database of lectin characterizations, clinical correlates and citations on the Internet.

Programmed and curated by Peter D'Adamo.

Copyright 2001-2011.

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Total number of records: 619 Matching records: 1

Homo sapiens :
Annexin IV

Molecular structure of
:Annexin IV

Homo sapiens

Lecster ID:354 Edit Entry
Source Organism:
Species:Homo sapiens
Common Nomenclature:Annexin IV
Index Nomenclature:ANNh.Hom.Sap.xx.Xxx4
Characterization Notes:The localization sites of annexin IV in the major expression tissues, the kidney and pancreas, and the result of in vitro binding assay of several glycoconjugates suggest that annexin IV is involved in the formation of apical sorting (secretory) vesicles due to the interaction with some GPI-anchored glycoproteins and proteoglycans.
Biological Activity:Activated leukocyte cell adhesion molecule (ALCAM) and annexin II are involved in the metastatic progression of tumor cells after chemotherapy with Adriamycin. See: Clin Exp Metastasis 2000;18(1):45-50
Source Tissue:
Specificity:Annexin IV was identified as a lectin binding to carbohydrate moieties of sialoglycoproteins and glycosaminoglycans in the presence of calcium
References:Bioessays. 2001 Feb;23(2):170-8. Review.

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By Peter D'Adamo. Copyright 2001-2011.