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Molecular structure of
|Lecster ID:354|| Edit Entry |
| Common Nomenclature:||Annexin IV|
|Characterization Notes:||The localization sites of annexin IV in the major expression tissues, the kidney and pancreas, and the result of in vitro binding assay of several glycoconjugates suggest that annexin IV is involved in the formation of apical sorting (secretory) vesicles due to the interaction with some GPI-anchored glycoproteins and proteoglycans.|
|Biological Activity:||Activated leukocyte cell adhesion molecule (ALCAM) and annexin II are involved in the metastatic progression of tumor cells after chemotherapy with Adriamycin. See: Clin Exp Metastasis 2000;18(1):45-50|
|Specificity:||Annexin IV was identified as a lectin binding to carbohydrate moieties of sialoglycoproteins and glycosaminoglycans in the presence of calcium|
|References:||Bioessays. 2001 Feb;23(2):170-8. Review.|
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By Peter D'Adamo. Copyright 2001-2011.