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LECSTER is the largest, open-access searchable database of lectin characterizations, clinical correlates and citations on the Internet.

Programmed and curated by Peter D'Adamo.

Copyright 2001-2011.

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Total number of records: 619 Matching records: 1

Homo sapiens :
Alpha-6 / Beta-7 integrin

Molecular structure of
:Alpha-6 / Beta-7 integrin

Homo sapiens

Lecster ID:337 Edit Entry
Source Organism:
Species:Homo sapiens
Common Nomenclature:Alpha-6 / Beta-7 integrin
Class:Integrin A (or I) domain
Index Nomenclature:INTh.Hom.Sap.xx.Xxxx
Characterization Notes:The alpha4/beta7 integrin is a receptor for MadCAM, fibronectin and VCAM-1. This integrin is only found leukocytes which are directed to the Peyer's Patches of the gut. MadCAM which is an addressin, is only found on Peyer's Patch Endothelium. The alpha4/beta7 integrin is also known as (LPAM-1). Data show that protein synthesis-dependent upregulation of the functional beta7 integrin occurs under conditions when beta4 and beta1 integrins are fully expressed, indicating a sequential appearance of specific adhesion molecules on differentiating eosinophil progenitors. See: Allergy 2000 Sep;55(9):865-72
Biological Activity:
Source Tissue:

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2015-3-3: Current Date 22:55:43 GMT: Current Time

By Peter D'Adamo. Copyright 2001-2011.