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LECSTER is the largest, open-access searchable database of lectin characterizations, clinical correlates and citations on the Internet.

Programmed and curated by Peter D'Adamo.

Copyright 2001-2011.

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Total number of records: 619 Matching records: 1

Homo sapiens :
Alpha-5 / Beta-3 integrin

Molecular structure of
:Alpha-5 / Beta-3 integrin

Homo sapiens

Lecster ID:333 Edit Entry
Source Organism:
Species:Homo sapiens
Common Nomenclature:Alpha-5 / Beta-3 integrin
Class:Integrin A (or I) domain
Index Nomenclature:INTh.Hom.Sap.xx.Xxxx
Characterization Notes:AlphaV/beta3 is a receptor for fibrinogen, fibronectin, von Willebrand's factor, Vitronectin, Tsp (Thrombospondin), osteopontin and Bsp1 (bone sialoprotein 1). It is expressed on endothelial cells, some B-cells, platelets and monocytes. alphaVb-beta3 mediates platelet aggregation and endothelial cell adhesion to ECM proteins. This integrin is also known as VNR (vitronectin receptor)
Biological Activity:
Source Tissue:

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2015-3-4: Current Date 11:37:5 GMT: Current Time

By Peter D'Adamo. Copyright 2001-2011.