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Homo sapiens :
Alpha-5 / Beta-3 integrin
|
Molecular structure of
:Alpha-5 / Beta-3 integrin
| 
Homo sapiens
|
| Lecster ID:333 | Edit Entry |
| Source Organism: | |
| Species: | Homo sapiens |
| Common Nomenclature: | Alpha-5 / Beta-3 integrin |
| Class: | Integrin A (or I) domain |
| Index Nomenclature: | INTh.Hom.Sap.xx.Xxxx |
| Characterization Notes: | AlphaV/beta3 is a receptor for fibrinogen, fibronectin, von Willebrand's factor, Vitronectin, Tsp (Thrombospondin), osteopontin and Bsp1 (bone sialoprotein 1). It is expressed on endothelial cells, some B-cells, platelets and monocytes. alphaVb-beta3 mediates platelet aggregation and endothelial cell adhesion to ECM proteins. This integrin is also known as VNR (vitronectin receptor) |
| Biological Activity: | |
| Source Tissue: | |
| Specificity: | |
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2013-5-22: Current Date 9:9:30 GMT: Current Time
By Peter D'Adamo. Copyright 2001-2011.
