LECSTER LECTIN DATABASE










LECSTER is the largest, open-access searchable database of lectin characterizations, clinical correlates and citations on the Internet.


Programmed and curated by Peter D'Adamo.

Copyright 2001-2011.



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Total number of records: 619 Matching records: 1

Homo sapiens :
Alpha-M / Beta-2 integrin



Molecular structure of
:Alpha-M / Beta-2 integrin

Homo sapiens



Lecster ID:331 Edit Entry
Source Organism:
Species:Homo sapiens
Common Nomenclature:Alpha-M / Beta-2 integrin
Class:Integrin A (or I) domain
Index Nomenclature:INTh.Hom.Sap.xx.Xxxx
Characterization Notes:AlphaM/beta2 is a receptor for C3bi (inactivated form of C3b), factor X (coagulation factor X), fibrinogen and ICAM-1 (intercellular adhesion molecule 1). It is expressed on monocytes, macrophages, NK cells and granulocytes. Alpha-M/beta-2 is important in adherence of monocytes and neutrophils to vascular endothelium, as well as in sebsequent extravasation. It also plays a role in phagocytosis of complement coated particles. This integrin is also known as Mac-1 (macrophage receptor 1) and CR-3 (C3bi receptor).
Biological Activity:
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2014-10-25: Current Date 20:47:20 GMT: Current Time

By Peter D'Adamo. Copyright 2001-2011.