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Homo sapiens :
Alpha-5 / Beta-1 integrin
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Molecular structure of
:Alpha-5 / Beta-1 integrin
| 
Homo sapiens
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| Lecster ID:324 | Edit Entry |
| Source Organism: | |
| Species: | Homo sapiens |
| Common Nomenclature: | Alpha-5 / Beta-1 integrin |
| Class: | Integrin A (or I) domain |
| Index Nomenclature: | INTh.Xxx.Xxx.xx.Xxxx |
| Characterization Notes: | Alpha5/beta1 is a receptor for fibronectin. It is expressed on Memory-T-cells, monocytes, platelets and fibroblasts. This integrin is also known as VLA-5 (very late activation antigen 5), FNR (fibronectin receptor), GPIc-IIa (glycoprotein Ic-IIa on platelets) and ECMRVI (extracellular matrix receptor VI). AlphaV/beta1 is a receptor for fibronectin. ntegrins alpha5beta1, alphavbeta1, and alphavbeta6 collaborate in squamous carcinoma cell spreading and migration on fibronectin. See: Exp Cell Res 2000 Feb 25;255(1):10-7 |
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2013-5-25: Current Date 6:55:31 GMT: Current Time
By Peter D'Adamo. Copyright 2001-2011.
