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Homo sapiens :
Mannose-Specific Endocytosis Receptor
|
Molecular structure of
:Mannose-Specific Endocytosis Receptor
| 
Homo sapiens
|
| Lecster ID:298 | Edit Entry |
| Source Organism: | |
| Species: | Homo sapiens |
| Common Nomenclature: | Mannose-Specific Endocytosis Receptor |
| Class: | |
| Index Nomenclature: | LECh.Hom.Sap.xx.Xma1 |
| Characterization Notes: | A plasma-membrane receptor expressed by rabbit alveolar macrophages that recognizes glycoprotein ligands bearing terminal mannose, fucose or N-acetylglucosamine residues.that recognizes glycoprotein ligands bearing terminal mannose, fucose or N-acetylglucosamine residues. |
| Biological Activity: | |
| Source Tissue: | |
| Specificity: | The purified protein binds mannose-BSA (bovine serum albumin) with a dissociation constant of 1.9 X 10(-8) M. |
| Inhibitors: | The binding of 125I-mannose-BSA is inhibited by ligands bearing high-mannose oligosaccharides, such as mannan or beta-glucuronidase, as well as the monosaccharides mannose, fucose and N-acetylglucosamine. Galactose, galactosylated BSA, glucose and mannos |
| References: | Biochem J 1987 Aug 1;245(3):705-11 |
2013-5-25: Current Date 22:28:3 GMT: Current Time
By Peter D'Adamo. Copyright 2001-2011.
