LECSTER LECTIN DATABASE










LECSTER is the largest, open-access searchable database of lectin characterizations, clinical correlates and citations on the Internet.


Programmed and curated by Peter D'Adamo.

Copyright 2001-2011.



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Total number of records: 619 Matching records: 1

Homo sapiens :
Mannose-Specific Endocytosis Receptor



Molecular structure of
:Mannose-Specific Endocytosis Receptor

Homo sapiens



Lecster ID:298 Edit Entry
Source Organism:
Species:Homo sapiens
Common Nomenclature:Mannose-Specific Endocytosis Receptor
Class:
Index Nomenclature:LECh.Hom.Sap.xx.Xma1
Characterization Notes:A plasma-membrane receptor expressed by rabbit alveolar macrophages that recognizes glycoprotein ligands bearing terminal mannose, fucose or N-acetylglucosamine residues.that recognizes glycoprotein ligands bearing terminal mannose, fucose or N-acetylglucosamine residues.
Biological Activity:
Source Tissue:
Specificity:The purified protein binds mannose-BSA (bovine serum albumin) with a dissociation constant of 1.9 X 10(-8) M.
Inhibitors:The binding of 125I-mannose-BSA is inhibited by ligands bearing high-mannose oligosaccharides, such as mannan or beta-glucuronidase, as well as the monosaccharides mannose, fucose and N-acetylglucosamine. Galactose, galactosylated BSA, glucose and mannos
References:Biochem J 1987 Aug 1;245(3):705-11





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2014-9-1: Current Date 11:46:11 GMT: Current Time

By Peter D'Adamo. Copyright 2001-2011.