LECSTER LECTIN DATABASE










LECSTER is the largest, open-access searchable database of lectin characterizations, clinical correlates and citations on the Internet.


Programmed and curated by Peter D'Adamo.

Copyright 2001-2011.



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Total number of records: 619 Matching records: 1

Geodia cydonium : Sponge




Molecular structure of
Sponge:

Geodia cydonium



Lecster ID:249 Edit Entry
Source Organism:Sponge
Species:Geodia cydonium
Common Nomenclature:
Class:
Index Nomenclature:LECi.Geo.Cyd.xx.Xga1
Characterization Notes:
Biological Activity:In the histochemical system GCA displayed no blood group specificity and labeled red blood cells, the vascular endothelium, and epithelial cells showing blood group antigen expression independent of the ABH blood group status. However, inhibition of GCA reactivity by simple sugars and complex carbohydrate s demonstrated tissue-specific differences of lectin binding related to the ABH blood group status of the tissue and revealed information on the structural requirements of the histological lectin binding site. Tissues that totally lacked blood group antigens or that expressed only the H-antigen disclosed a GCA reactivity which was completely inhibited by lactose. In contrast, tissues that expressed blood group A- or blood group B-antigen exhibited a lactose-resistant lectin binding which was inhibited only by water-soluble blood group substance A from peptone A and by bovine glycophorin but not by other complex carbohydrate s, including human glycophorin and human asialoglycophorin. See: J Histochem Cytochem 1991 Apr;39(4):491-505
Source Tissue:
Specificity:D-galactose
Inhibitors:
References:Eur J Biochem 1983 Jun 15;133(2):263-7





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2014-4-25: Current Date 9:8:3 GMT: Current Time

By Peter D'Adamo. Copyright 2001-2011.