LECSTER LECTIN DATABASE
LECSTER is the largest, open-access searchable database of lectin characterizations, clinical correlates and citations on the Internet. Programmed and curated by Peter D'Adamo. Copyright 2001-2011.
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Didemnum candidum : Oyster DTL, DCL-I, DCL-II
Molecular structure of Oyster:DTL, DCL-I, DCL-II
Didemnum candidum
Lecster ID:202 Edit Entry Source Organism: Oyster
Species: Didemnum candidum Common Nomenclature: DTL, DCL-I, DCL-II
Class:
Index Nomenclature: LECi.Did.Sss.xx.Xga1
Characterization Notes: Didemnum ternatanum lectin (DTL) is specific for N-Acetyl-D-glucosamine. Didemnum candidum lectins (DCL-I, DCL-II) possesses lectin activity directed toward galactosyl moieties.
Biological Activity: Although both DCL-I and DCL-II will agglutinate neuraminidase -treated erythrocytes from all vertebrate species tested and most Pronase-treated erythrocytes , DCL-I will agglutinate some untreated erythrocytes which are not agglutinate d by DCL-II.
Source Tissue:
Specificity: galactosyl groups
Inhibitors: In hemagglutination inhibition assays among the mono- and oligosaccharides tested, N-acetyl-d-glucosamine, N, N'-diacetylchitobiose, N,N'N"-triacetylchitotriose were the most potent inhibitors.
References: DTL: Biochim Biophys Acta 1998 Apr 10;1380(2):249-56 DCL-I and DCL-II: J Biol Chem 1986 Jul 15;261(20):9182-6
2013-5-18: Current Date 23:16:10 GMT: Current Time
By Peter D'Adamo. Copyright 2001-2011.