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|Cytisus scoparius : Scotch broom|
CSA-I, CSA-II, CMH-I, CMH-II
Molecular structure of
Scotch broom:CSA-I, CSA-II, CMH-I, CMH-II
|Lecster ID:189|| Edit Entry |
|Source Organism:||Scotch broom|
| Common Nomenclature:||CSA-I, CSA-II, CMH-I, CMH-II|
|Index Nomenclature:||LECp.Cyt.Sco.se.Hga1 (CS-I) LECp.Cyt.Sco.se.Hga2 (CS-II)|
|Characterization Notes:||Two anti-H(O) lectins were separated from extracts of Cytisus sessilifolius seeds by successive affinity chromatographies on columns of di-N-acetylchitobiose- and galactose-Sepharose 4B. One was found to be inhibited most by di-N-acetylchitotriose or tri-N-acetylchitotriose [Cytisus-type anti-H(O) lectin designated as Cytisus sessilifolius lectin I (CSA-I)] and the other anti-H(O) lectin was inhibited by galactose or lactose and designated as Cytisus sessilifolius lectin II (CSA-II).|
|Biological Activity:||CSA-I and CSA-II agglutinate blood group H(O) erythrocytes, as does CMH-I. CMH-II is a non-blood group specificy hemagglutinin.|
|Inhibitors:||CMH-I is inhibited by di- N-acetylchitobiose or tri- N-acetylchitotriose. Treatment of human O erythrocytes with a purified H-decomposing enzyme (alpha-L-fucosidase from Bacillus fulminans abolished the agglutinability of the cells with CMH-I. This indi|
2014-11-1: Current Date 7:35:37 GMT: Current Time
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