PATHbase
A database of blood type linked pathology.


DiseaseCoronary artery disease
Blood Group LinkIn a study of 191 coronary artery bypass candidates, investigators paradoxically found and excess of Type O over Type A. When they examined the data more closely, they concluded that that the tendency of Type A to develop blood clots more readily ("thrombotic proneness") caused a poorer prognosis. In essence, the Type As were missing from the study because they had already died in greater numbers, leaving a disproportionate excess of Type Os among the long term survivors.
Special NoteABH non-secretors have a higher incidence of heart disease, but paradoxically with the subtypes higher incidence of alcoholism, the effects of alcohol are most protective in this group as well.
References1. Erikssen J, Thaulow E, Stormorken H, Brendemoen O, Hellem A. ABO blood groups and coronary heart disease (CHD). A study in subjects with severe and latent CHD. Thromb Haemost 1980 Jun 18;43(2):137-140

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