Sprue also known as celiac sprue and celiac disease, it is an inherited disease in which the intestinal lining is inflamed in response to the ingestion of a protein known as gluten. Treatment of celiac disease involves the avoidance of gluten, which is present in many grains, including rye, oats, and barley. Inflammation and atrophy of the lining of the small intestine leads to impaired nutrient absorption. |