7-keto DHEA means there is a ketone link between the 7th and 8th carbon molecule on dehydroepiandosterone. Big deal?? Acually, its changes the biochemistry dance...
The therapeutic properties of 7-Keto DHEA are very similar to those of DHEA. The primary difference between 7-Keto DHEA and regular DHEA is that the anabolic properties of DHEA are maximized while the androgenic effects (which are problematic) are minimized with 7-Keto DHEA. There are also claims that 7-Keto DHEA is more potent in terms of therapeutic effects compared to regular DHEA:
Unlike regular DHEA, 7-Keto DHEA is NOT transformed into Testosterone or Estrogens. All of the studies that have been conducted to date indicate that supplemental 7-Keto DHEA is entirely safe:

- The impressive safety profile of supplemental 7-Keto DHEA is highly likely to be due to its inability to be converted within the body to further Hormones (e.g. Testosterone, Estrogens).
- Human studies have demonstrated the absolute safety of supplemental 7-Keto DHEA at doses of 200 mg per day (in men aged 18 to 49).

I'm not a huge fan of hormones (and DHEA in any form is banned in Australia). I got some for my Mum once but thats about all I have ever used it.

I could go into more biochemical detail but hopefully this should answer your question.

Regards,
Stephen.