This is a product which contain chemicals called glyconutrients. There are more than 8 however, there are 8 that are considered "essential" for health. Aloe is however only one source of many. The best source is colostrum (the early whey fraction from cow's milk), or mother's milk. All the medical studies are done on this source. Other sources include soy, peanuts, many herbs etc. I have heard the hype about the product but it dosen't stack up biochemically. Most glyconutrients don't even get absorbed. This makes them useful for gut detox. In one of our products we have them in to act as "decoy sugars". The "bad" bugs attach to such sugars found at receptor sites in the gut. If you consume these mono, di, oligo, or polysaccharides, the "bad" bugs think there attached to the gut, yet are passed through the gut without adherence to the gut wall. Nifty eh!! I believe gut dysbyosis is one of the major causes of illness thus glyconutrients can help in a large range of illnesses. We have been using them for more that 8 years now, but when Manatech started telling stories of cures for all sorts of diseases, including cancer, we sold out of our product!!! Ed is right about the multi level stuff. You end up paying for the "levels" and not the product.
If you want to use aloe, just use the juice. Its cheaper and more effective as the Ayurvedic doctors have been using it for thousands of years to treat gut "ama" (toxins).
As for the glyconutrients and ER4YT, well it depends on the food you eat to get them. eg. soy.
Oh, and don't buy into the fact that they are the only ones with these sugars/monosaccharides etc. There are hundreds of sources. And no, they can't patient a plant, only the extraction method. Yes, I have heard the tapes released by them. As for helping receptor activity, and helping cells communicate, possible, but the journals don't show it (unless you read one released by Mannatech themselfs!!)