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BTD Forums  /  Live Right 4 Your Type  /  Genetics and secretor status
Posted by: susanC, Thursday, June 5, 2014, 8:29pm
Can someone out there explain the genetics of secretor status to me.  Is one status dominant over the other?

My son (B) and his wife (A) have both popped up as nonnies.  Drat.  Does this mean that their children are likely to be nonnies as well?
Posted by: Captain_Janeway, Friday, June 6, 2014, 3:45am; Reply: 1
Non-secretor is recessive to secretor. Which means both your son and his wife carry two copies of the non-secretor gene (se). So yes any children they have will be non-secretors.


If one parent is a secretor and the other is a non-secretor then the offspring can be either secretors or non-secretors depending on the genotype of the secretor parent.


In all cases everyone has two copies of a gene one from each parent. So a nonnie is always se/se because its a recessive trait but a secretor can be Se/Se or Se/se.
Posted by: susanC, Friday, June 6, 2014, 4:50am; Reply: 2
Quoted from Captain_Janeway
Non-secretor is recessive to secretor. Which means both your son and his wife carry two copies of the non-secretor gene (se). So yes any children they have will be non-secretors.


If one parent is a secretor and the other is a non-secretor then the offspring can be either secretors or non-secretors depending on the genotype of the secretor parent.


In all cases everyone has two copies of a gene one from each parent. So a nonnie is always se/se because its a recessive trait but a secretor can be Se/Se or Se/se.


Thank you much CJ for the explanation.

Posted by: Lola, Friday, June 6, 2014, 7:38am; Reply: 3
cj is on the dot! :)
Posted by: Easy E, Tuesday, June 10, 2014, 3:54pm; Reply: 4
http://www.sandimaswellness.com/files/Secretor_or_Non-Secretor.pdf
Posted by: Dianne, Tuesday, June 10, 2014, 4:23pm; Reply: 5
Quoted from Captain_Janeway
Non-secretor is recessive to secretor. Which means both your son and his wife carry two copies of the non-secretor gene (se). So yes any children they have will be non-secretors.


If one parent is a secretor and the other is a non-secretor then the offspring can be either secretors or non-secretors depending on the genotype of the secretor parent.


In all cases everyone has two copies of a gene one from each parent. So a nonnie is always se/se because its a recessive trait but a secretor can be Se/Se or Se/se.


Captain Janeway : Thank you for this explanation. Makes me wonder as I've done the saliva secretor test twice as I thought perhaps they mixed mine and my husband's. Both times I came out as secretor and he a nonnie, which greatly surprised us both. I fit more the description of nonnie that you see on the board here that he does. Impossible where I live to get the Lewis Phenotyping unless I required a transplant of some sort. But...still feel I may be a nonnie...both of my parents had a difficult time with their teeth - my mother was told she had the jaw of a Viking, but her teeth were in a bad state. She had dentures by the time she was 20. My father's teeth were all removed by the time I was 8. Makes me wonder if they were both nonnies, which would make me one as well? I sure wish I could get that blood test, sigh.  :)
Posted by: Captain_Janeway, Tuesday, June 10, 2014, 7:47pm; Reply: 6
Quoted from Dianne


Captain Janeway : Thank you for this explanation. Makes me wonder as I've done the saliva secretor test twice as I thought perhaps they mixed mine and my husband's. Both times I came out as secretor and he a nonnie, which greatly surprised us both.



Diane, the secretor status kit that is  now available at DPN (formerly NAP) is a genomic based test that utilizes DNA technology (PCR) from a sample of cheek cells.  The test incorporates the use of  sequence specific primers to test for the presence or absence of the Se gene and  it effectively determines secretor genotype if you are Se/Se, Se/se or se/se.

I had this test back in March of this year and it positively correlated with my Lewis blood group phenotype.

The kit is very easy to use and requires no saliva just cheek cells from a swab.

Roughly about 78% of Caucasians are secretors. Other populations will vary.

Posted by: susanC, Wednesday, June 11, 2014, 3:21pm; Reply: 7
Quoted from Dianne


Captain Janeway : Thank you for this explanation. Makes me wonder as I've done the saliva secretor test twice as I thought perhaps they mixed mine and my husband's. Both times I came out as secretor and he a nonnie, which greatly surprised us both. I fit more the description of nonnie that you see on the board here that he does. Impossible where I live to get the Lewis Phenotyping unless I required a transplant of some sort. But...still feel I may be a nonnie...both of my parents had a difficult time with their teeth - my mother was told she had the jaw of a Viking, but her teeth were in a bad state. She had dentures by the time she was 20. My father's teeth were all removed by the time I was 8. Makes me wonder if they were both nonnies, which would make me one as well? I sure wish I could get that blood test, sigh.  :)


Diane--My B nonnie son (35) has had excellent teeth.  One filling in his mouth at about age 21.  But mind you, as a baby/child growing up he had so many health issues that just had me scratching my head and sometimes wanting to pull my hair out.  It was sure no surprise to me to find he was a nonnie a few years ago.  But teeth remain healthy.  So I guess all nonnies don't have bad teeth.

Posted by: Dianne, Thursday, June 12, 2014, 12:11am; Reply: 8
Captain Janeway - thanks for that, the test is not offered in my country because the contact here for Dr. D'Adamo says that he cannot find a lab that will do the test. Perhaps in the future if I go to the U.S. I shall have it sent there and do the test and mail in while there also.  :)

SusanC - You are so right, it definitely is not a hard and fast rule.  :)
Posted by: misspudding, Thursday, June 12, 2014, 1:22am; Reply: 9
I think part of the thing with teeth, is that the water where you live, assuming you drink enough of it, will have suspended mineral content. I grew up in one of the best areas for natural fluoride and calcium carbonate in the water (SE Missouri/Southern Illinois/Western Kentucky).

http://www.museum.state.il.us/exhibits/symbols/mineral.html

I have near perfect teeth. Not entirely sure I'm a nonnie, but have a lot of nonnie characteristics. Same with my hubby. But we grew up in areas blessed with natural bone-building minerals everywhere you looked. My son is growing up in an area completely deficient in all of that. And his teeth are awful.
Posted by: Easy E, Thursday, June 12, 2014, 11:29am; Reply: 10
I find the tap where i live in south louisiana really helps my stomach in terms of acid reflux.  I started drinking the tap instead of bottled water and now i need nothing for acid reflux and do not get it unless certain times of spring or take in something that makes my sinus's drip.  It is high Ph hard water with plenty of calcium and magnesium.
Posted by: Amazone I., Wednesday, June 18, 2014, 7:24am; Reply: 11
Easy E... must correct ya a little... :B :D... but please take notice and become aware about this very fact: often in A's & AB's we can remark a symptom of acid reflux but in reality it isn't this at all but low stomach acidity which causes the same effects...symptoms.... I once observed one of my A-clients taking Bullrich's salts... and do you know what the ingredient do??) ;)... they don't diminish but augment stomach acidity...so far he did the right thing but his expectations were wrong ;) (funny)(shrug)(oh)(hehe)
Posted by: PCUK-Positive, Wednesday, June 18, 2014, 8:11am; Reply: 12
Fascinating that an AB parent doesn't always pass on to a AB child.

I know the mechanics of why it is possible that they can have a A, B or AB Child, but still kind of weird.
Posted by: Easy E, Wednesday, June 18, 2014, 3:35pm; Reply: 13
In my family, my dad is AB, my mom is O, my sis is B, and i am A!  How's that for weird?

Amazone:  i think eating superfoods and limiting avoids (now coffee too...again) helps more than anything.  The water is good but it's definately not the only thing that helped.  I don't have any trouble with the acid reflux these days.  It is working whatever i am doing, and i replaced coffee with tea now, that was the only thing left that aggravated it.
Posted by: Amazone I., Wednesday, June 18, 2014, 4:08pm; Reply: 14
:D(smarty)(clap)(ok) ;D
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