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BTD Forums  /  The GenoType Diet  /  MTHFR Gene
Posted by: Christopher1, Saturday, November 17, 2012, 12:54am
I tested heterozygous for MTHFR. What does this mean? My doctor wasn't too helpful.

Does this mean I make little glutathione? (Sure is great news after hearing I'm a non-secretor as well. :-/)
Posted by: C_Sharp, Saturday, November 17, 2012, 1:33am; Reply: 1
This means you have a single copy of a gene for an enzyme that effects glutathione metabolism. This means the activity of this key enzyme in is at 55% to 70% of people with a normal MTHFR enzyme.

There are over 50 variant of the gene depending which abnormality you have will influence the effect.




You probably want to supplement with Methyl B12.

You should try to eat a diet with foods rich in folic acid.

Your ability detoxify is weak so try to avoid toxins in the diet as well as exposure to environmental toxins.

If getting SWAMI from practitioner, be sure to advice them of this condition so they can make appropriate adjustments to the diet recommendations.
Posted by: Christopher1, Saturday, November 17, 2012, 5:25pm; Reply: 2
Quoted from C_Sharp
This means you have a single copy of a gene for an enzyme that effects glutathione metabolism. This means the activity of this key enzyme in is at 55% to 70% of people with a normal MTHFR enzyme.

There are over 50 variant of the gene depending which abnormality you have will influence the effect.




You probably want to supplement with Methyl B12.

You should try to eat a diet with foods rich in folic acid.

Your ability detoxify is weak so try to avoid toxins in the diet as well as exposure to environmental toxins.

If getting SWAMI from practitioner, be sure to advice them of this condition so they can make appropriate adjustments to the diet recommendations.


Exactly. My DO ordered B12 injections for me to take.

I asked him about methylfolate.

He said: "No, it's too soon."

Whatever that means...
Posted by: AKArtlover, Saturday, November 17, 2012, 8:38pm; Reply: 3
Quoted Text
He said: "No, it's too soon."

Whatever that means...


I think it might mean that there is a specific order in which you incorporate what you are doing as you are setting off a series of biochemical reactions. Ask questions!
Posted by: Christopher1, Monday, November 19, 2012, 6:03pm; Reply: 4
Quoted from AKArtlover


I think it might mean that there is a specific order in which you incorporate what you are doing as you are setting off a series of biochemical reactions. Ask questions!


Will do!
Posted by: C_Sharp, Saturday, March 30, 2013, 4:13pm; Reply: 5
Methylation, MTHFR gene, and Cancer

http://www.blogtalkradio.com/mthfrsupport/2013/03/28/methylation-mthfr-and-cancer
Posted by: Lola, Saturday, March 30, 2013, 5:32pm; Reply: 6
http://www.dadamo.com/cgi-bin/Blah/Blah.pl?b-GTDdiet/m-1202698596/#num13
Posted by: Amazone I., Wednesday, April 3, 2013, 9:21am; Reply: 7
C-sharp....nothing but (clap)(ok)(dance)(smarty) thanx for shahring... I also found these infos and guys talking about the problem... and what else also is important.. the active form of B12 seems to be contrainduced !!! ........dito  B9 as a single product... therefor I always recomended the B-complex in higher dosages ....
Posted by: readingyourlips, Friday, September 19, 2014, 6:36am; Reply: 8
I just found out I am homozygous for the C677T mutation. As far as secreter status, Itested years ago when the test kit first came out and came back with secreter, but there is a ppossibility that a little blood from my gums may have gotten in there. Would that impact the results?

Not sure whatit means in regard to my type o diet. Any thoughts?

Steph
Posted by: PCUK-Positive, Friday, September 19, 2014, 9:56am; Reply: 9
Quoted from Christopher1


Exactly. My DO ordered B12 injections for me to take.

I asked him about methylfolate.

He said: "No, it's too soon."

Whatever that means...


Isn't that a bit extreme, why not just take a b12 sup. I take Dr D's it's very effective It's called methyl 12 Plus  It also has Folate (as Folic Acid)-(I'm Homozygous for Methylenetetrahydrofolate Reductase (MTHFR)

http://www.4yourtype.com/prodinfo.asp?number=NP008
Posted by: deblynn3, Friday, September 19, 2014, 3:06pm; Reply: 10
Quoted from Christopher1


Exactly. My DO ordered B12 injections for me to take.

I asked him about methylfolate.

He said: "No, it's too soon."

Whatever that means...


http://beyondmthfr.com/2014/09/09/mthfr-and-sibo/

Just went through a week webclass.  (whatever their called, I'm brain fogged today) Got a lot of studying to do.  Yourare to take the b12 (and a complex) before the methylfolate because the methylfolate will detox you faster and all your symptoms will increase. At least that's the best way I can put it. The site above might help.
Posted by: misspudding, Friday, September 19, 2014, 3:59pm; Reply: 11
More recent discussion where we've discussed all of this and with great links:

http://www.dadamo.com/cgi-bin/Blah/Blah.pl?m-1410150072/
Posted by: Chloe, Friday, September 19, 2014, 8:40pm; Reply: 12
http://genetics.thetech.org/ask/ask425
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