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BTD Forums  /  Live Right 4 Your Type  /  BT that changes due to bone marrow transplant...
Posted by: O in Virginia, Tuesday, January 17, 2012, 12:31am
I keep thinking about what my aunt old me recently when I was visiting her and her family in November.  I asked her what her blood type was - my grandparents were A- and O-, so I knew it had to be one of those.  She told me that she was an A, but that her blood type had changed to O after she had had a bone marrow transplant to treat leukemia.  The transplant was successful because she is still here many years later to tell the tale.  But she has had many health issues, and I wonder why they wouldn't have found a donor with bone marrow of the same blood type?  Is it possible she is mistaken?  Does this actually happen, that a person's blood type can change?  I can't get this out of my head.  It really bothers me.   :-/  I feel so sorry for her because she has suffered all kinds of health problems that I wonder, had she had her own type A bone marrow transplanted, whether they would have been as devastating.
Posted by: PCUK-Positive, Tuesday, January 17, 2012, 12:47am; Reply: 1
I believe it is one of the few reasons or times that blood type changes, but I have a feeling it was to do with the cancer and not the donors blood type. I read something about it, but it was a while ago so I can't remember the detail.
Posted by: ruthiegirl, Tuesday, January 17, 2012, 1:17am; Reply: 2
So what BTD should a person in that situation follow? The blood type they now have, or the blood type they were born with?
Posted by: DoS, Tuesday, January 17, 2012, 2:01am; Reply: 3
Is it bad that I sorta want a bone marrow transplant if I could be O+? Although I don't know if it would make my body change to act like a regular Type O.
Posted by: C_Sharp, Tuesday, January 17, 2012, 2:17am; Reply: 4
Quoted from DoS
Is it bad that I sorta want a bone marrow transplant if I could be O+? Although I don't know if it would make my body change to act like a regular Type O.


Forget about this $100,000 option.

Even if you change the blood type in your veins, the cells in your digestive system are still going to have your original DNA. Thus they will express the original blood type antigen.  It is the secretions in the digestive track and what is expressed on cell surfaces in the digestive track that more affects what one should eat rather than the type of blood coursing through the veins.
Posted by: Lola, Tuesday, January 17, 2012, 3:17am; Reply: 5
gut bacteria also has antigens......
Posted by: TJ, Tuesday, January 17, 2012, 6:37am; Reply: 6
Quoted from ruthiegirl
So what BTD should a person in that situation follow? The blood type they now have, or the blood type they were born with?
She'd still best follow the A diet since that is genetically her type, and the A gene would have had its normal influences on her digestive, immune, and other systems.

FYI, a person with type O couldn't change to type A, B, or AB, because the A and B antigens would appear foreign and the immune system would attack them.  It's the same principle as with blood transfusions, except that the "new" blood is being made in the body instead of being injected into the body.
Posted by: O in Virginia, Tuesday, January 17, 2012, 8:15am; Reply: 7
Yes, I do see that it would have to have been an O "universal donor" transplant, in lieu of an acceptable Type A donor, which was not found in her own family.  So, if she is still Type A on a DNA/cellular and gut bacterial level, then the O blood type she has now is not really an issue?   ??)  Very interesting.  Perhaps she would be best on those foods mutually benenficial to As and Os.  I would love to convince her to follow BTD.
Posted by: PCUK-Positive, Tuesday, January 17, 2012, 8:25am; Reply: 8
a mutually low lectin diet. olive oil, turkey, cod, ....
Posted by: O in Virginia, Tuesday, January 17, 2012, 8:28am; Reply: 9
Quoted from PCUK-Positive
a mutually low lectin diet. olive oil, turkey, cod, ....


Yes, I think you're right.  Thank you.
Posted by: chrissyA, Tuesday, January 17, 2012, 4:01pm; Reply: 10
The husband of a friend of mine was Type O originally, and now is Type A after a bone marrow transplant. I puzzled and puzzled over this, coming to the conclusion that maybe he was stating it backwards, but it was a procedure that saved his life, he wouldn't get the facts backwards (duh). So I asked my bro, who is a Dr., and he referred me to his wife who works in the blood lab, who was able to explain the whole thing in a way that I could understand. But don't ask what she said, I wouldn't be able to relate it effectively. But yes, it most certainly can happen that way. Who knew?!?! :o
Posted by: O in Virginia, Tuesday, January 17, 2012, 11:42pm; Reply: 11
Quoted from chrissyA
The husband of a friend of mine was Type O originally, and now is Type A after a bone marrow transplant. I puzzled and puzzled over this, coming to the conclusion that maybe he was stating it backwards, but it was a procedure that saved his life, he wouldn't get the facts backwards (duh). So I asked my bro, who is a Dr., and he referred me to his wife who works in the blood lab, who was able to explain the whole thing in a way that I could understand. But don't ask what she said, I wouldn't be able to relate it effectively. But yes, it most certainly can happen that way. Who knew?!?! :o


Wow, I wouldn't imagine it could be done the reverse way, O to A.  This is so strange.  How has your friend's husband's health been subsequently?
Posted by: DoS, Wednesday, January 18, 2012, 12:58am; Reply: 12
Quoted from C_Sharp


Forget about this $100,000 option.

Even if you change the blood type in your veins, the cells in your digestive system are still going to have your original DNA. Thus they will express the original blood type antigen.  It is the secretions in the digestive track and what is expressed on cell surfaces in the digestive track that more affects what one should eat rather than the type of blood coursing through the veins.


Yeah so I figured... except cells do reproduce and die. When you get a pig valve it acclimates to your body after awhile. My thought was maybe when signaling for cells to come anew, they get signaled by something that requests/designates different protein binding sites so the body no longer sees it as foreign. So I think anything is possible even if this is not.
Posted by: Seraffa, Wednesday, January 18, 2012, 6:40am; Reply: 13
Quoted from DoS
Is it bad that I sorta want a bone marrow transplant if I could be O+? Although I don't know if it would make my body change to act like a regular Type O.


Smiles - have you ever had ANY transplants before? You just talked about pig valves.

All I can say is I'm utterly flabbergasted by this whole bone marrow transplant thing. Life as an A/O "ever afterwards" must be.....astounding...but I'm just getting this crawly feeling all over my body thinking of what the recipient's body must go thru.....scares me.
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