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BTD Forums  /  Live Right 4 Your Type  /  the genetics of secretor status
Posted by: angela, Monday, June 8, 2009, 2:48am
my parents have both taken the secretor test and have come out as secretors. does anyone know whether this means i'm also a secretor? i thought i was anyhow just based on the recommended foods, etc.--just trying to figure out if it's worth springing for the tst. it probably is  ::)

Posted by: Lloyd, Monday, June 8, 2009, 2:54am; Reply: 1
Since the nonnie gene is recessive you could still be nonnie. Kind of like blue eyes from brown eyed parents. It happens.
Posted by: C_Sharp, Monday, June 8, 2009, 2:54am; Reply: 2
Nonsecretor is a recessive trait.

Therefore if both parents are secretors, a child could be a secretor or a nonsecretor.

If both parents were nonsecretors than the child will be a nonsecretor.
Posted by: Vicki, Monday, June 8, 2009, 9:48am; Reply: 3
You'll have to test to find out your secretor status.  I'm a non-secretor born of two secretor parents.  

In the below Punnett Square, similar to a multiplication table, I show the possible outcomes from a pairing of two Secretor parents.

A gene is made up of two alleles.  Offspring receive one allele from each parent.  

Se represents the secretor allele.

se represents the non-secretor allele.


In the followig example, I assume that each parent has a recessive non-secretor (se) allele.  They are both secretors (Se) therefore they also each have a secretor (Se) allele.



The four outcomes include:

1) Se Se - two Se alleles combine to make one a Secretor

2) Se se - Se and se alleles combine to make one a Secretor

3) Se se - Se and se alleles combine to make one a Secretor

4) se se - two se alleles combine to make one a Non-secretor

In the above example, each child of this paring would result in a 3/4 chance of being a secretor and a 1/4 chance of being a non-secretor.

Stay tuned, for the example where only one parent has a recessive non-secretor allele and the example where both parents have all secretor alleles.  
Posted by: Vicki, Monday, June 8, 2009, 9:59am; Reply: 4
In the below Punnett Square, similar to a multiplication table, I show the possible outcomes from a pairing of two Secretor parents.

A gene is made up of two alleles.  Offspring receive one allele from each parent.  

Se represents the secretor allele.

se represents the non-secretor allele.


In the followig example, I assume that one parent has a recessive non-secretor (se) allele.  They are both secretors (Se).  The mother has two Secretor (Se) alleles and the father has one Secretor (Se) and one Non-secretor (se) allele.  



The four outcomes include:

1) Se Se - two Se alleles combine to make one a Secretor

2) Se Se - two Se alleles combine to make one a Secretor

3) Se se - Se and se alleles combine to make one a Secretor

4) Se se -Se and se alleles combine to make one a Secretor

In the above example, each child of this paring would result in a Secretor.

Stay tuned - one more possibility for the parents!
Posted by: Vicki, Monday, June 8, 2009, 10:06am; Reply: 5
Final possibility for two secretor parents:

In the below Punnett Square, similar to a multiplication table, I show the possible outcomes from a pairing of two Secretor parents.

A gene is made up of two alleles.  Offspring receive one allele from each parent.  

Se represents the secretor allele.

se represents the non-secretor allele.


In the followig example, I assume that both parent have two dominant Secretor (Se) alleles.  They are both secretors (Se).  The mother has two Secretor (Se) alleles and the father has two Secretor (Se) alleles.



The four outcomes include:

1) Se Se - two Se alleles combine to make one a Secretor

2) Se Se - two Se alleles combine to make one a Secretor

3) Se Se -  two Se alleles combine to make one a Secretor

4) Se Se - two Se alleles combine to make one a Secretor

In the above example, each child of this paring would result in a Secretor.
Posted by: Vicki, Monday, June 8, 2009, 10:06am; Reply: 6
Let me know of any typos!  
Posted by: angela, Monday, June 8, 2009, 5:19pm; Reply: 7
thanks for the info--that definitely makes sense. off to order my test  :P
Posted by: Amazone I., Monday, June 8, 2009, 6:04pm; Reply: 8
and I was persuated that it might be that if one of the parents is a so called *silent* nonnie, he/she only carries the gen.... the offsprings might /will be nonies... ok in my case I am nearly sure that all members of that blo...families were nonnies...  all too weird for not being...haaa...anything else.... :o :-/ :P :P :(
Posted by: Vicki, Tuesday, June 9, 2009, 2:20am; Reply: 9
One day I'll find out my siblings secretor status!

:-)
Posted by: ruthiegirl, Friday, August 19, 2011, 10:16pm; Reply: 10
So it follows that if both parents are non-secretors, all the kids will be non-secretors as well?
Posted by: SandrAruba, Friday, August 19, 2011, 11:21pm; Reply: 11
I think my mom is also a nonnie and my father was a secretor.
Posted by: AKArtlover, Friday, August 19, 2011, 11:26pm; Reply: 12
Being a little lazy, but does anyone know what the actual gene marker is for this? Or location, etc.? I don't know the terminology yet. :)
Posted by: Spazcat, Saturday, August 20, 2011, 12:38am; Reply: 13
I'm guessing both my parents are secretors and carry the nonnie gene that I so luckily inherited.  My parents and both brothers are as strong as oxen and I seem to be a bit more fragile.  My parents are 89 years old with relatively minor health issues and have consumed wheat and coffee their whole lives (dad is O, mom doesn't know her blood type).  I hope my nonnie-ness doesn't cancel out all the good things I must have inherited from them!
Posted by: C_Sharp, Saturday, August 20, 2011, 12:38am; Reply: 14
Quoted from AKArtlover
does anyone know what the actual gene marker is for this? Or location, etc.?

FUT2
Chromosome 19
Location: 19q13.3
Posted by: Vista, Saturday, August 20, 2011, 7:31am; Reply: 15
ABH blood group secretor status: http://www.snpedia.com/index.php/Rs601338

ABH blood group secretor status if Japanese: http://www.snpedia.com/index.php/Rs1047781

http://www.snpedia.com/index.php/Rs504963

http://www.snpedia.com/index.php/Rs602662

Higher B12 levels in women, related to FUT2:

http://www.snpedia.com/index.php/Rs492602


http://www.snpedia.com/index.php/FUT2
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