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BTD Forums  /  Live Right 4 Your Type  /  ABO Gut Immunology & Peyer's Patches
Posted by: Harry O, Tuesday, May 28, 2013, 9:06pm
I just watched an animation about how our gut immunology works and so they'd mentioned the regions throughout the gut called the ''Peyer's Patches'' that do the ''sampling'' of the antigens (food, bacteria etc.) that enter all along the intestinal tract and so i'm wondering if that is the part of our intestines where our ABO resides at as Dr D has researched that we have more ABO in our guts than in our blood?

Very cool animation (6:51 length) for those interested.
Posted by: Adopted4, Wednesday, May 29, 2013, 11:53pm; Reply: 1
Very interesting video; lots of terminology I've never heard before.
Posted by: Lola, Thursday, May 30, 2013, 5:54am; Reply: 2
Blood Type Diet Movies #4: "Substance"!
Posted by: Lola, Thursday, May 30, 2013, 5:58am; Reply: 3
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    Lymphoid tissue is found in those areas where immune activity is constantly required, such as the appendix, tonsils and Peyer's Patches of the intestines, areas which ...

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role for mucin in what is called 'recognition phenomena;' the cellular 'homing' of lymphocytes (from areas such as the tonsils in the throat or Peyer's Patches

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It is in the Peyer's Patches that you build up immune tolerance to foods, or conversely, intolerance. A striking association is that celiac disease predisposes patients
Posted by: Harry O, Friday, May 31, 2013, 9:16pm; Reply: 4
Quoted from Lola

Awesome Lola ... as i read your posted links !!

So then now my understanding about it is that our ''gut ABO'' is located in the mucin which is composed of mucopolysaccharides (ABO Type) that covers our entire intestinal tract hence it would come in contact with anything (food, bacteria, parasites etc.) that enters into it.

If i'm wrong then please correct me here.

Again thank you Lola !!
Posted by: Lola, Sunday, June 2, 2013, 6:21am; Reply: 5
thought you might like this by Dr D, on your question

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link between inflammation and glycosylation:

    Peter D'Adamo Now this is interesting. This seems to be linking inflammation with changes in sialylation/desialylation of o-linked mucins. If you've
been to IFHI or read the GM textbook this should peak your interest: the T and Tn pancarcinoma family of blood group antigens are two premiere O-linked
glycans, which like very much to play with EGF (herceptin target). Now, it gets even more interesting. Changes to T and Tn are linked to the progression of
many inflammatory conditions (UC for example). We also know that in general the more inflammatory the breast cancer the more aggressive. Thus we have two
mechanisms behind breast cancer prognosis that link to O mucin aberrant glycosylation: infiltration and inflammation. Broad beans, mushrooms, amaranth and
escargot tend to induce redifferentiation of Tn and T; peanuts tend to encourage it.
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