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BTD Forums    Diet and Nutrition    The GenoType Diet  ›  General consensus on 23andme? *
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General consensus on 23andme? *
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Brimstone
Sunday, January 8, 2017, 11:42am Report to Moderator Report to Moderator

Explorer, super taster
Autumn: Harvest, success.
Posts: 128
Gender: Female
Location: Suffolk, England
Age: 46
Before the forum closes I was just wondering what the general consensus was on the 23andme?
I've only just come across it and haven't been tested as yet but think it's something I would like to know in the near future when funds allow...but, I shall most likely have it done when this forum in sadly no more...
...so, just want to glean as much info from your great minds before that day comes...
So, how has it made a difference to your lives and what information would be good for me to know.
Just dipping my tiny toe in, but it all sounds pretty complicated to the uninitiated...that's me...at the mo.
Am also looking for someone to tell me about it in plain English as I'm a bit overwhelmed with all the terminology and jargon.
Hope some of you will be happy to guide me.
Thank you.
Also, sorry if I have posted this in the wrong place...

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C_Sharp  -  Saturday, January 14, 2017, 10:21pm
Added * to thread title to indicate Dr. D. commented in the thread
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Lola
Sunday, January 8, 2017, 4:03pm Report to Moderator Report to Moderator

GT1; L (a-b-); (se); PROP-T; NN
Sa Bon Nim
Admin & Columnist
Posts: 53,567
Gender: Female
Location: ''eternal spring'' Cuernavaca - Mex.
Age: 60
you have one of the experts close-by

contact Tom Greenfield for targeted advice and follow-through


''Just follow the book, don't look for magic fixes to get you off the hook. Do the work.'' Dr.D.'98
DNA mt/Haplo H; Y-chrom/J2(M172);ESTJ
The harder you are on yourself, the easier life will be on you!
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C_Sharp
Sunday, January 8, 2017, 7:06pm Report to Moderator Report to Moderator

Teacher Rh+ Lewis: a+b-, NN,Taster
Sa Bon Nim
Administrator
Posts: 9,497
Gender: Male
Location: Illinois
Age: 56
I do not know what you want the 23 & Me data for.

If it is not for something specific like Opus 23 & Me, then you need to to do the test that is going to provide the desired information in the desired format.

If you do not have a specific use for the information then you may want to save your money.

If you want/enjoy working with genetic info, then you may want to consider more complete testing available from companies using more recent procedures.

For instance Genos Research test the whole exome instead of selected SNPs (which is what 23 & Me does).

https://genos.co/order.html




MIfHI                            I follow a SWAMI diet.
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C_Sharp
Sunday, January 8, 2017, 8:45pm Report to Moderator Report to Moderator

Teacher Rh+ Lewis: a+b-, NN,Taster
Sa Bon Nim
Administrator
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Gender: Male
Location: Illinois
Age: 56
Quoted from Brimstone

So, how has it made a difference to your lives and what information would be good for me to know.


Endless entertainment value. No end of data to look at.  Analyzing the vast pile of information from 23 & Me could keep fully occupied for this lifetime and the next.

Have gotten no practical or useful information from 23 & Me test results (tested 6 years ago).



MIfHI                            I follow a SWAMI diet.
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Mrs T O+
Sunday, January 8, 2017, 9:50pm Report to Moderator Report to Moderator

Concealed Carry Gatherer! SWAMI Explorer Blend
Kyosha Nim
Posts: 4,206
Gender: Female
Location: Chicago, Illinois
Age: 69
I found some useful info lIke what nationalities I might be. Some of that is guessing. I found out I had a big chunk of Italian which is cool. The Greek was mixed in with Balkan. So even tho those countries seem different than Greece to me, apparently the DNA ( or whatever genetic material there is) is similar. There was a smattering of other nearby countries' genetic results, but no real surprises. Someone else may find they are part something they had no idea of.
Then it gave info of what diseases I might be prone to. The 2 major ones are not in my family at all, but it was interesting to know. It also gave chances of Alzheimer's. Since that had become more common, it it nice to know. For somebody, that might be more than worth the price of the test!

I don't have a powerful computer to read all the details, but I got the major things.
There were several groupings of letters that are supposed to mean something thst I don't understand, like A-B+  For various classifications, like Diego blood group.....  A professional could read those.
Still, for my 99 bucks, I got a good amount of info. I really wanted to know the nationalities I am and this was helpful. The only danger is that even tho your info is confidential, there is no guarantee someone could get a hold of it in later years to blackmail or try to control people.


Interested in nutrition, lactation, religion, politics; love to be around people; talkative, sensitive, goofy; fishy Christian ><>; left-handed; lived on a farm, small town & big city; love BTD/GTD;  La Leche League veteran; b. 10/1947 Check BTD/GTD on facebook!
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Brimstone
Monday, January 9, 2017, 7:03am Report to Moderator Report to Moderator

Explorer, super taster
Autumn: Harvest, success.
Posts: 128
Gender: Female
Location: Suffolk, England
Age: 46
Recently I was diagnosed with thyroid disease.
My mum then had to get tested and her antibodies are raised but other thyroid test results are ok which means she will have to be tested regularly.
Anyway, the reason I asked about the genetic testing is that my mum was an abandoned baby and we have no clue to the family line on her side, I just thought that even with having no family history we could find out possibly if there was any genetic info that could be useful.
Which is why when it turned out I had thyroid disease she had to be tested...funny that it wasn't the other way round...
Anyway thanks for all your replies, I think it's something that I may look into further...I think it will help with my detectoring.
Thank you 🙂
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Dr. D
Monday, January 9, 2017, 9:41am Report to Moderator Report to Moderator

Peter D'Adamo
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A whole system is a living system is a learning system.’ -Stewart Brand
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Averno
Monday, January 9, 2017, 1:21pm Report to Moderator Report to Moderator

Swami Warrior
Kyosha Nim
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Location: Maryland
Quoted Text
Opus23 is a suite of apps that provide a development environment for generative precision medicine.
It allows the clinician to import raw genomic data (such as provided by 23andMe and other services)


Is Genos one of the "others" that can be imported into Opus23?

If so, does Genos provide a more accurate or detailed Opus23 report?

Does Genos provide ancestry data (to the extent that 23 and Me does)?
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Mrs T O+
Tuesday, January 10, 2017, 2:19am Report to Moderator Report to Moderator

Concealed Carry Gatherer! SWAMI Explorer Blend
Kyosha Nim
Posts: 4,206
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Location: Chicago, Illinois
Age: 69
Brimstone, I think it would be great if your mum could get tested. I would be very curious to know my ancestry and disease possibilities.
I think a lot of folks have thyroid problems because we don't have enough iodine and have too much fluoride and chloride in our environment. There are a coupe of other "ides" that affect the iodine. Filters can get rid of chlorine, but you need a more expensive one to get rid e fluoride we are forced to have in our tap water.


Interested in nutrition, lactation, religion, politics; love to be around people; talkative, sensitive, goofy; fishy Christian ><>; left-handed; lived on a farm, small town & big city; love BTD/GTD;  La Leche League veteran; b. 10/1947 Check BTD/GTD on facebook!
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Brimstone
Tuesday, January 10, 2017, 6:21am Report to Moderator Report to Moderator

Explorer, super taster
Autumn: Harvest, success.
Posts: 128
Gender: Female
Location: Suffolk, England
Age: 46
Thanks Dr D for posting the link, am glad I'd have to go through a pro with this one...
...blimey Charlie...looks crazy and amazing all at the same time...
...the fantasmatron sounds particularly intriguing!
I guess I need to get clued up a little and give DrThom a ring.

Hey Mrs T, I think you're right about the iodine and the fluoride...have been reading about this lately and have bought some lugols iodine but haven't started it yet...also am having fluoride free toothpaste although I'm not entirely sure if fluoride is added to our water here or not...will check.
Anyway yes it's scary how many people are being effected by thyroid disease and the numbers keep rising by all accounts.
I don't think Mum will go for the opus but I'm very interested to find out my genetics.
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Lola
Tuesday, January 10, 2017, 6:46am Report to Moderator Report to Moderator

GT1; L (a-b-); (se); PROP-T; NN
Sa Bon Nim
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Posts: 53,567
Gender: Female
Location: ''eternal spring'' Cuernavaca - Mex.
Age: 60
Quoted Text
Does Genos provide ancestry data (to the extent that 23 and Me does)?


I believe Dr D is focusing on 23&me data results to input into Opus23 , not genos


''Just follow the book, don't look for magic fixes to get you off the hook. Do the work.'' Dr.D.'98
DNA mt/Haplo H; Y-chrom/J2(M172);ESTJ
The harder you are on yourself, the easier life will be on you!
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C_Sharp
Tuesday, January 10, 2017, 2:52pm Report to Moderator Report to Moderator

Teacher Rh+ Lewis: a+b-, NN,Taster
Sa Bon Nim
Administrator
Posts: 9,497
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Quoted from Lola


I believe Dr D is focusing on 23&me data results to input into Opus23 , not genos


That is correct.  But unless the intention is to get Opus 23, than there appears to be little reason to use use the old 23 & Me approach of testing selected SNPs versus testing the whole exome which is offered by other vendors.



MIfHI                            I follow a SWAMI diet.
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cajun
Tuesday, January 10, 2017, 8:12pm Report to Moderator Report to Moderator

Teacher/Explorer
Ee Dan
Posts: 3,151
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Location: Southern California
Age: 65
Just my 2 cents....
I am glad I did 23andme to find a first (once removed) cousin in Canada...one I had never met.
Her dad is my first cousin...his dad and my dad are brothers.
Amazing that we shared DNA on nearly every chromosome!!!!!
Like MrsT, I found ethnicities I hadn't known about! I knew some Italian and French/Spanish Basque
but had no clue about the small percentage of Finnish and the larger amount of Balkan!
Also,
They update my health reports constantly as new research is done. Carrier status is informative!
Thank goodness I am not a carrier for any of the very serious, dreaded diseases...some rare.
Apparently, my parents passed on only the best of themselves to me.


 Ao  ISFJ   Taster   Rh+  

"God gave us the gift of life. It is up to us to give ourselves the gift of living well." Voltaire
"Whisper words of wisdom. Let it be." Sir Paul McCartney
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Averno
Tuesday, January 10, 2017, 10:07pm Report to Moderator Report to Moderator

Swami Warrior
Kyosha Nim
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Thank you Lola and C_Sharp  
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RedLilac
Friday, January 13, 2017, 4:14pm Report to Moderator Report to Moderator

SWAMI tweaked Explorer Super Taster from Illinois
Kyosha Nim
Posts: 3,137
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Location: Lombard, Illinois (Chicago suburb)
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My son, 1st Cousin & myself did it years ago right before they stopped the health analysis.   I found out interesting information.  I connected with distant cousins.  I uploaded my data to other sites.  I'm glad I did it.


I am B- NON-Sec Explorer; my son is B+ SEC Nomad; my Mother was O+; and my Father was AB-
SWAMI Thanksgiving present 2008
Revised from Arlene B- NonSec to RedLilac on 3/31/06
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Dr. D
Saturday, January 14, 2017, 11:31am Report to Moderator Report to Moderator

Peter D'Adamo
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Age: 60
There is no problem with Genos data, other than the sheer size. However, except for isolated instances, more is generally only more. This is due to the knowledge gap between what can be discovered and what is known. Reporting a new SNP is not difficult; it simply requires some patience and the necessary technology. Being able to draw some sort of meaningful conclusion from the SNP is a much, much bigger deal. Now you have to do the epidemiological work, which is   involved, complicated and expensive. For example, 23andme reports about 700,000 snps. Of these, we know 'something' about around 7,000, while we are able to draw actionable conclusions on closer to 3000 - 4000.

Of the rest? Black hole.  Granted, though,  there are some cool SNPs not reported by 23andme, or buried in the 'i' (internal ids) numbers versus the conventional 'rs' id number.



A whole system is a living system is a learning system.’ -Stewart Brand
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