Hi does anyone know what dr d take is in the MTHFR mutation gene ? Thanks a bunch

this is of interest to me also as I have been doing my own research on it due my personal issues…..

Title not what I thought it was

Dr. D: a true Mother-Father-Gentleman

Quoted from lisa

Hi does anyone know what dr d take is in the MTHFR mutation gene ? Thanks a bunch

Dr. D. uses the MTHFR gene in SWAMI GenoType. When you get SWAMI done by a professional, one of the settings the practitioner makes is whether a client has an MTHFR mutation.  

Setting MTHFR to either one or two copies of the mutation changes the diet recommendations.

The consumer version of SWAMI (SWAMI Xpress) does not have an MTHFR option.

listen to this audio

#14 http://www.4yourtype.com/MEDIA_audio.asp#

and also

#10 http://www.4yourtype.com/MEDIA_audio.asp#

My son was just tested and is homozygous, so got a copy from both his dad and I. I would argue we're all classic explorers (all O, my son and I are O neg).

It basically means you break stuff down way slower than normal, because folate is one of the ways the liver detoxes things out of your body. Less folate, more sensitive to smaller amounts of drugs and toxins.

The other thing that stinks is it raises your inflammation if you're not eating enough folate. This can totally set off autoimmunity. In my son's case, he was just diagnosed with Crohns. I believe I'm a mild Crohns sufferer, as I've had what I can only describe as "flares" in the past, which I just assumed was celiac/gluten sensitivity.

Soooo...it's not something to mess around with. Make sure you're getting plenty of greens, and beans and brown rice, if you can handle it. And once you think you've eaten enough greens, eat more greens.  

Also, avoid folic acid! It competes with folate in the body, and if you're MTHFR, you do a really awful job of converting it to the active form in the body. Stick with food, if you can, but if you need supplemental, first start with some methyl B-12 for, like, a month, and then start up some methyl folate in very small doses. It can backfire if you go too quickly. And if you have any overgrowth that is causing inflammation, it can exacerbate it, so suck down some ginger, turmeric, and fish oil at the same time!

Quoted from Eric

Title not what I thought it was

HA ha ha!!

this is the new elephant in the room….I really hope Dr. D takes it on in all its complexity!!! We need a researcher like him and a brain like him to tackle the ins and outs of it.

There are so many combinations of SNPs …its so individual (that word again)….like you need all those greens but not if you have the CBS mutation and can't process sulfur….etc….

This whole business is why I have insomnia and have for years…sometimes better, sometimes worse….taking the folate keeps me awake at night if it's too much…you have to get the folate up but not too fast.

Ahhh, the sulfur. Bummer! I think I'm okay on that front, as I haven't noticed problems with, say, Epsom salts or salads. Very complicated, indeed!

Is it still possible to get the SNP info from 23andme if you were to do the testing now?

as far as I know…then you put the info thru genetic genie (google it)…free…gives much more info.

Epsom salts and salads don't bother me, but eggs, and crucferous veggies do also NAC, milk thistle, etc. I still eat eggs, but not as many…and I stay away from loads of cooked greens. The way to find out is to get sulfur strips to test urine. It's not that obvious otherwise. They say lots of meat too, but I eat plenty and it doesn't give problems.

Good to know!

I'm Homozygous, partner is Negative and DD is Heterozygous just to keep it simple NOT lol

homo is pretty serious…I'm hetero and have issues….

MTHFR very significant in Teacher Genotypes, less so in others. In fact, the a polymorphisms in MTHFR may well be beneficial in Hunters as the small amount of homocysteine acts as a 'pro-oxidant' resulting in greater production of the Hunter's own internal antioxidants through a mechanism called 'hormesis'.

wanted to share this info although I haven't read it all myself.  Just an interesting take from people
who have tried various methylation protocols. I need to educate myself.  I just found my genetic
test results done in 2003 that show ++ MTHFR gene variant. Yikes!!  Of course, these people chatting aren't aware of their genotype, but still, interesting to read their discussion.

http://forums.phoenixrising.me.....2012-revision.19050/

Something else worth noting...the relationship between magnesium and MTHFR.  I can't seem to retain
magnesium....I'm, starting to understand why!

http://gotmag.org/mg-deficiency-affects-mthfr-really/

A whole website devoted to MTHFR
http://mthfr.net/

Quoted from Dr. D

MTHFR very significant in Teacher Genotypes, less so in others. In fact, the a polymorphisms in MTHFR may well be beneficial in Hunters as the small amount of homocysteine acts as a 'pro-oxidant' resulting in greater production of the Hunter's own internal antioxidants through a mechanism called 'hormesis'.

Nice to know we can relax a bit as Dr D is taking ALL into account in swami Pro.

Thanks Dr D.

According to what I have read recently in 23andme, MTHFR can have something to do with Parkinsons Need to read all of their latest info.
My dad has Parkinsons and he believes his mother had it also.
I need to put my data through the genie as Jayneeo suggested.

yes, the results for Parkinson's and Alzheimer's will appear "locked" on 23 and me, you just click on it to see results. They don't want to frighten anyone suddenly.

Thanks  

I am hetero which helps explain my toxic levels of lead and mercury.  The problem is, at least in my case, when I tried chelation therapy it shut down ALL methylation and I had to go off the chelation protocol.  I'm not sure what I can do to detox the stuff safely . . .

Quoted from Patty H

I am hetero which helps explain my toxic levels of lead and mercury.  The problem is, at least in my case, when I tried chelation therapy it shut down ALL methylation and I had to go off the chelation protocol.  I'm not sure what I can do to detox the stuff safely . . .

Patty, I just found this....very interesting...I didn't do well on chelation either...I am hetero too...but
feeling less freaked out when I read this is a copying error rather than a true genetic defect.

SWAMI gives most of us many cups of green vegetables...According to this, eating greens is a great solution.

http://drlwilson.com/ARTICLES/FOLIC%20ACID%20DEFECTS.htm

Eating cilantro will detox heavy metals

http://www.naturalnews.com/027942_cilantro_heavy_metals.html

...so will pectin...Modified Citrus Pectin  http://www.econugenics.com/sho.....aZsb4CFQJeOgodjUYApQ

I'm s'posed to take chelation also…but am hesitant….high lead and cadmium. I've heard cilantro doesn't do what we wish…but can pull toxins out of tissue only to circulate around...