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Trehalose & candida albicans?  This thread currently has 1,561 views. Print Print Thread
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Dianne
Tuesday, February 7, 2012, 2:57am Report to Moderator Report to Moderator

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I myself no longer have candida but I know someone who was taking a product that had a blend of essentials sugars from some company and it greatly exacerbated their candida.

I am wondering if Trehalose is alright for people who suffer with candida.
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Andrea AWsec
Tuesday, February 7, 2012, 3:01am Report to Moderator Report to Moderator

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Call D'Adamo Personalized Nutrition and ask about it then let us know.


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brinyskysail
Tuesday, February 7, 2012, 3:44am Report to Moderator Report to Moderator

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trehalose is a disaccharide of two glucose molecules, and yeasts definitely like glucose.  The genoma trehalose complex has about 3 grams of trehalose per serving so using it as a supplement might not be a big deal, but - like anything else - excessive use is probably not a good idea.


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DoS
Tuesday, February 7, 2012, 4:30am Report to Moderator Report to Moderator

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Quoted from brinyskysail
trehalose is a disaccharide of two glucose molecules, and yeasts definitely like glucose.  The genoma trehalose complex has about 3 grams of trehalose per serving so using it as a supplement might not be a big deal, but - like anything else - excessive use is probably not a good idea.


Except we don't know that yeast, bacteria, or anything can digest it. Remember the human body can't.
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Christopher1
Tuesday, February 7, 2012, 5:38am Report to Moderator Report to Moderator

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So??? Glucose is good. Immune process to get rid of Candida requires plentiful glucose. Running on ketones solely will make your Candida worse and will starve your gut bacteria. I've made this mistake, thinking a low carb diet would help me get rid of Candida. Wrong! White rice is particularly benign source of glucose. Candida loves ketones.

I hate Candida, lol.
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C_Sharp
Tuesday, February 7, 2012, 5:44am Report to Moderator Report to Moderator

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Quoted from DoS


Except we don't know that yeast, bacteria, or anything can digest it. Remember the human body can't.


Typically humans digest trehalose more slowly than some other saccharides, but they do digest it.

The trehalose molecule is cleaved into two glucose molecules and the glucose is broken down like glucose from any other source.

If a person is trehalase deficient they will have difficulties breaking down trehalose. This is a relatively rare condition.

Many varieties of yeast and bacteria can digest trehalose.  Literature is available that indicates which species can and cannot digest trehalose. Some bacteria use trehalose as a storage carbohydrate.  

Prior to the corn starch method of producing trehalose, yeast were often used to create trehalose, but the corn starch method is much cheaper than using yeast the both create and break down trehalose.
    


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Lola
Tuesday, February 7, 2012, 7:33am Report to Moderator Report to Moderator

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like the sugar in deflect glucosamine
trehalose might also be considered a 'sacrificial sugar'....

meaning, it would not mess with candida, in fact, do just the opposite


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brinyskysail
Tuesday, February 7, 2012, 11:58am Report to Moderator Report to Moderator

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http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0015808

There's a lot going on in this article so it's not just simply trehalose or lack of trehalose, but it does seem to infer that trehalose (at least trehalose produced by C. albicans) is protective to the yeast.  I don't know if trehalose from an external source would be different.

Quoted Text
Trehalose accumulation in C. albicans has been described
as a defense mechanism against oxidative stress. A trehalosedeficient
tps1D mutant is highly sensitive to H2O2 and prone to
undergo phagocytic digestion [31]. However, the mechanism by
which trehalose protects C. albicans from injuries remains unclear.
Since apoptosis is now considered as one of the important ways of
C. albicans death, we assessed the role of trehalose in H2O2-induced
apoptosis using a tps1g mutant. According to our result, lack of
trehalose could accelerate H2O2 -induced apoptosis which was
accompanied by an increase of ROS, an apoptosis indicator. This
result revealed a mechanism for the protective role of trehalose in
C. albicans. Similar results were reported by other researchers"


Also found this for C. albicans:

Fermentation Reactions: Where fermentation means the production of gas and is independent of pH changes.

Positive: Glucose; Maltose.
Variable: Galactose; Trehalose.
Negative: Sucrose (some strains positive); Lactose.

Assimilation Tests:

Positive: Glucose; Maltose; Galactose; Trehalose; Sucrose (some negative); D-Xylose; Soluble Starch; D-Mannitol; D-Glucitol (Delayed).
Variable: Melezitose; Glycerol; Succinic acid; L-Arabinose; L-Sorbose; D-Ribose (some positive); Citric acid; DL-Lactic acid.
Negative: Potassium nitrate; Lactose; Ribitol (some positive); Raffinose; Cellobiose; Melibiose; Erythritol; Inositol; L-Rhamnose; D-Arabinose; Galactitol; Salicin.

http://www.mycology.adelaide.edu.au/Fungal_Descriptions/Yeasts/Candida/Candida_albicans.html


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Chloe
Tuesday, February 7, 2012, 3:28pm Report to Moderator Report to Moderator

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