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BTD Forums    Diet and Nutrition    Live Right 4 Your Type  ›  ABO Gut Immunology & Peyer's Patches
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Harry O
Tuesday, May 28, 2013, 9:06pm Report to Moderator Report to Moderator

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I just watched an animation about how our gut immunology works and so they'd mentioned the regions throughout the gut called the ''Peyer's Patches'' that do the ''sampling'' of the antigens (food, bacteria etc.) that enter all along the intestinal tract and so i'm wondering if that is the part of our intestines where our ABO resides at as Dr D has researched that we have more ABO in our guts than in our blood?

Very cool animation (6:51 length) for those interested.
http://www.youtube.com/watch?v=gnZEge78_78

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Harry O  -  Tuesday, May 28, 2013, 9:29pm
Harry O  -  Tuesday, May 28, 2013, 9:28pm
Harry O  -  Tuesday, May 28, 2013, 9:27pm
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Adopted4
Wednesday, May 29, 2013, 11:53pm Report to Moderator Report to Moderator

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Very interesting video; lots of terminology I've never heard before.


Coleen ISF-J, Non-Taster
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Lola
Thursday, May 30, 2013, 5:54am Report to Moderator Report to Moderator

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Lola
Thursday, May 30, 2013, 5:58am Report to Moderator Report to Moderator

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Quoted Text
    Lymphoid tissue is found in those areas where immune activity is constantly required, such as the appendix, tonsils and Peyer's Patches of the intestines, areas which ...


Quoted Text
role for mucin in what is called 'recognition phenomena;' the cellular 'homing' of lymphocytes (from areas such as the tonsils in the throat or Peyer's Patches


Quoted Text
It is in the Peyer's Patches that you build up immune tolerance to foods, or conversely, intolerance. A striking association is that celiac disease predisposes patients


http://www.dadamo.com/btdisease/PathType-read.pl?show=30
http://www.dadamo.com/btdisease/PathType-read.pl?show=117
http://www.dadamo.com/science_endotoxins_allergens.htm


''Just follow the book, don't look for magic fixes to get you off the hook. Do the work.'' Dr.D.'98
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Harry O
Friday, May 31, 2013, 9:16pm Report to Moderator Report to Moderator

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Quoted from Lola


Awesome Lola ... as i read your posted links !!

So then now my understanding about it is that our ''gut ABO'' is located in the mucin which is composed of mucopolysaccharides (ABO Type) that covers our entire intestinal tract hence it would come in contact with anything (food, bacteria, parasites etc.) that enters into it.

If i'm wrong then please correct me here.

Again thank you Lola !!
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Lola
Sunday, June 2, 2013, 6:21am Report to Moderator Report to Moderator

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Sa Bon Nim
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thought you might like this by Dr D, on your question

Quoted Text
link between inflammation and glycosylation:
http://www.ncbi.nlm.nih.gov/pubmed/23150665?dopt=Citation

    Peter D'Adamo Now this is interesting. This seems to be linking inflammation with changes in sialylation/desialylation of o-linked mucins. If you've
been to IFHI or read the GM textbook this should peak your interest: the T and Tn pancarcinoma family of blood group antigens are two premiere O-linked
glycans, which like very much to play with EGF (herceptin target). Now, it gets even more interesting. Changes to T and Tn are linked to the progression of
many inflammatory conditions (UC for example). We also know that in general the more inflammatory the breast cancer the more aggressive. Thus we have two
mechanisms behind breast cancer prognosis that link to O mucin aberrant glycosylation: infiltration and inflammation. Broad beans, mushrooms, amaranth and
escargot tend to induce redifferentiation of Tn and T; peanuts tend to encourage it.


''Just follow the book, don't look for magic fixes to get you off the hook. Do the work.'' Dr.D.'98
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