I know that blood type-o is the oldest blood type however has Dr. D  ever mentioned if non secretor is older than secretor? Did secretor possibly mutate from non secretor? If so does that then mean that those of us who are blood type-o non secretors are the ancient blood type and there for the reason we seem to have to most health issues pertaining to auto immune and inflammation from an ancient immune system designed to fight the elements of when we were hunter gatherer's ??

I think i read somewhere that there are some  that think that the non secretror O's may be older but i do not have a link.

Quoted from Tall-O

Did secretor possibly mutate from non secretor?

I think this would be the case. Any mutation has to be a dominant gene or else it would simply be erased in an ocean of dominant original genes. I believe secretor is the dominant gene thus 'non' would be the original.

Quoted from shoulderblade

I think this would be the case. Any mutation has to be a dominant gene or else it would simply be erased in an ocean of dominant original genes. I believe secretor is the dominant gene thus 'non' would be the original.

O.k. thanks for that info Shoulderblade & Policychecker!

I don't think that any of us are old enough to know.  

perhaps we met in another life, no??

Another reason for supposing that non-secretor is older is that Explorer is the Genotype potentially available to every blood type.  Explorer is most likely nonnie-dominant, although I am married to a Secreting RH +ve Explorer.  Although Explorer is geographically limited, this universality of potential hints at an "Original Genotype."  The dominant secretor status of a likely "Original Genotype" must be old, itself.

Quoted from paul clucas

Although Explorer is geographically limited, this universality of potential hints at an "Original Genotype."  The dominant secretor status of a likely "Original Genotype" must be old, itself.

I follow your reasoning here but I am not sure what you mean by "Explorer is geographically limited". Are you saying, for instance that populations that are on the fringe of human population, like Northern Europeans for instance, are less likely to be Explorers or non-secretors? I think it might be a little more complicated than that.

I'm feeling old enough as it is!  Don't rub it in, guys!

Explorer is typically not Asian, but this is the current and transitory state of affairs.

Explorer is Mediterranian in the widest possible sense, including Northern Africa, the Levant and Caucus areas, as well as Europe.

Of course Genotyping is hardly done on a scale and spread for the data to be anything but suposition.

Quoted from Lola

perhaps we met in another life, no??

The more people I meet...the more I know this is true.

(((Big hugs)))

Debra

Somewhere I read that secretors developed after or the same time as some virus.  

O.k. so i assuming that since type-o secretors evolved after type-o 'non' secretors was the case and so now i'm guessing that since secretor status has been sequenced that the later blood types (a,b,ab) produced both non secretor and secretor at the same time.

I'm guessing that in the future some thousands of years from now that evolution will probably wipe out us blood type o ''non'' secretors first  

Quoted from Tall-O

I'm guessing that in the future some thousands of years from now that evolution will probably wipe out us blood type o ''non'' secretors first  

No way. As long as there is no evolutionary pressure on that particular gene(s) the ratio of types and secretor status will remain pretty well constant. Whatever pressures demanded a mutation to secretors has long passed so the consequences will remain in equilibrium.   Diversity is a priceless asset of the species.

Makes sense that nons would be the older one. We have more of  primative and limited diet. It seems as time goes on all the other blood types are mostly mutations of the most primative BT = o non.

Lately I have been thinking what if nonnies are not older?

It could be possible their advent was a response to world pressure. Think of it this way... the body is attacked by exorbitant amounts of lectins and faced with a lot of A and O mixing say with like the Basque... Now consider what happens when people get all wishy-washy on calories and mix it in with a less that perfectly stable womb environment.

What if what I am getting at is the possibility that a change occurred based on bodies giving up trying to fight off bad lectins? Much like bodies in turmoil that do not correctly make insulin.

Quoted from O plus

Makes sense that nons would be the older one. We have more of  primative and limited diet. It seems as time goes on all the other blood types are mostly mutations of the most primative BT = o non.

Think this would be true. When a mutation occurs not all individuals follow suit so eventually you get a collection of variations, Blood types, Rh-/+, sec/non etc. This would be especially true if a species were spread over a wide area as pressures that existed toward mutation would apply in some areas and not others.

Good for the species though as it builds up a wide variety of adaptations to confront future changes in the enviornment.

Quoted from shoulderblade

No way. As long as there is no evolutionary pressure on that particular gene(s) the ratio of types and secretor status will remain pretty well constant. Whatever pressures demanded a mutation to secretors has long passed so the consequences will remain in equilibrium.   Diversity is a priceless asset of the species.

Well at one time every person on earth (100%) was a type o non secretor (correct?). O.k. i believe that type o's are around 45% of the worlds population today and of that non secretors are only around 20% (Dr. D'adamo stats) and so that represents about only 9% of the worlds population today is type o ''non'' secretor as it sure seems like evolution is slowly booting us out  

Quoted from Tall-O

O.k. i believe that type o's are around 45% of the worlds population today and of that non secretors are only around 20% (Dr. D'adamo stats) and so that represents about only 9% of the worlds population today is type o ''non'' secretor as it sure seems like evolution is slowly booting us out  

The world is not trying to boot you out it's just trying to make you nervous.

First of all I think your numbers are a little optimistic. The US might be 45% O but I think for a global estimate this is a little high. I can't put up a specific figure but if you look at these distribution maps you will see that the Americas are, by global standards, rather high O and low A,B and AB. Given the higher populations and higher A-B levels in Asia I think the global level for O would be well below 45%. Will look into this further.

Global Blood Type Distribution

I also recall that the numbers for non-secretors is about 15%.

In any case once the pressures that instigate the mutations have subsided the relative numbers of the different types will remain stable unless some other crisis comes along to upset the balance. The dominant genes are dominant in a selected pair but are placed in pairs at random. Thus recessive genes, in sufficient numbers, can maintain their population even when outnumbered by multiples of their own levels. (i.e. given a stable enviornment O non numbers will remain at the same % for an endless time)

The diminishing of O-non numbers over the past say nothing in particular about the future.

O.k. i see now that i did select the number from the American Red Cross and didn't realise that it was for the USA only and i appreciate the posted link and correction as i see that the world percentage of type o shows 63%  although i could have swore that i've read in one of the books that Dr. D'adamo stated that non secretors are around 20%?

Anyway it still doesn't look too good for futuristic type o non secretors with the exception of a few isolated hunter/gatherer societies.

Thanks for those numbers Shoulderblade  

Quoted from Tall-O

Anyway it still doesn't look too good for futuristic type o non secretors with the exception of a few isolated hunter/gatherer societies.

Not necessarily. If you take any number of factors into account , say blood type, Rh factor and secretor status, everyone is tossed into a very minority situation, some are just newer than others. Whatever happened to the stressors that created new blood types, Rh+, secretors? Who knows. They are history and only the consequences remain.

Microbes are always evolving new ways to attack the human organism, even if not on purpose. If they decide to attack the immune system itself (i.e. HIV/Aids or maybe the 1918 Flu virus) having a 'primitive' immune system may prove to be an advantage as there is less there to mobilize to their advantage.

In any case O-non can sustain its present % in the human population unless some stressor comes along to challenge its position. In fact this would seem unlikely as that option has already occured in history. Other minority types are not going to expand at any other minorities expense for the time being.