Welcome, Guest.
Please login or register


Main Forum Page  ♦   Latest Posts  ♦   Member Center  ♦   Search  ♦   Archives   ♦   Help   ♦   Log In/Out   ♦   Admins
Forum Login
Login Name: Create a new account
Password:     Forgot password

BTD Forums    The Library    Journal Club and Literature Review  ›  Zonulin's "Identity", Leaky Gut, & Autoimmunity
Users Browsing Forum
No Members and 1 Guests

Zonulin's "Identity", Leaky Gut, & Autoimmunity  This thread currently has 2,873 views. Print Print Thread
1 Pages 1 Recommend Thread
TJ
Monday, February 7, 2011, 5:28pm Report to Moderator Report to Moderator

54% Nomad
Kyosha Nim
Posts: 3,486
Gender: Male
Location: Midvale, UT, USA
Age: 39
http://www.news-medical.net/news/20090908/Scientists-solve-the-mystery-of-zonulins-identity.aspx
Quoted Text
Scientists led by Alessio Fasano, M.D., have identified zonulin as a molecule in the human body called haptoglobin 2 precursor.

Quoted Text
"While apes, monkeys and chimpanzees do not have haptoglobin 2, 80 percent of human beings have it," says Dr. Fasano. "Apes, monkeys and chimpanzees rarely develop autoimmune disorders. Human beings suffer from more than 70 different kinds of such conditions. We believe the presence of this pre-haptoglobin 2 is responsible for this difference between species."

Quoted Text
In celiac patients, gluten generates an exaggerated release of zonulin that makes the gut more permeable to large molecules, including gluten. The permeable gut allows these molecules, such as gluten, access to the rest of the body. This triggers an autoimmune response in which a celiac patient's immune system identifies gluten as an intruder and responds with an attack targeting the intestine instead of the intruder. An inappropriately high level of production of zonulin also seems responsible for the passage through the intestine of intruders other than zonulin, including those related to conditions such as diabetes, multiple sclerosis and even allergies. Recently, other groups have reported elevated production of zonulin affecting the permeability of the blood brain barrier of patients suffering from brain cancer.
Logged Offline
Private Message Private message
Lola
Monday, February 7, 2011, 5:46pm Report to Moderator Report to Moderator

GT1; L (a-b-); (se); PROP-T; NN
Sa Bon Nim
Admin & Columnist
Posts: 51,282
Gender: Female
Location: ''eternal spring'' Cuernavaca - Mex.
Age: 57
yup......the gut, our second brain


''Just follow the book, don't look for magic fixes to get you off the hook. Do the work.'' Dr.D.'98
DNA mt/Haplo H; Y-chrom/J2(M172);ISTJ
The harder you are on yourself, the easier life will be on you!
Logged
Private Message Private message YIM YIM Reply: 1 - 3
Harry O
Monday, February 7, 2011, 8:09pm Report to Moderator Report to Moderator

Autumn: Harvest, success.
Posts: 203
Gender: Male
Age: 51
Interesting article and so thanks TJ !! Like lola always says ''heal the gut, heal the body''  
Logged Offline
Private Message Private message Reply: 2 - 3
Amazone I.
Monday, February 7, 2011, 8:20pm Report to Moderator Report to Moderator

Rh+ GT 4...E/..INTJ ....prop.=non-taster..
Kyosha Nim
Columnists and Bloggers
Posts: 16,334
Gender: Female
Location: CH-Benglen Kanton Z�rich
Age: 56
perhaps might be it more true to call our gut * our 2cond feelings* wisdom


MIfHI K-174
Logged
Private Message Private message Reply: 3 - 3
1 Pages 1 Recommend Thread
Print Print Thread

BTD Forums    The Library    Journal Club and Literature Review  ›  Zonulin's "Identity", Leaky Gut, & Autoimmunity

Thread Rating
There is currently no rating for this thread