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BTD Forums    Diet and Nutrition    The GenoType Diet  ›  Slow acetylators
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Slow acetylators  This thread currently has 4,139 views. Print Print Thread
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Magess
Monday, August 24, 2009, 3:09am Report to Moderator Report to Moderator

Explorer
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I wanted to send Dr. D a question, but I can't figure out how, so I thought I'd just ask the board.

How do you determine if you're a slow acetylator? I have high caffeine sensitivity, so I thought I could be one. Is that an accurate assumption?

And 2) what does being slow acetylator mean for alcohol consumption? Do they get drunker faster? Or stay drunk longer?
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Lola
Monday, August 24, 2009, 4:14am Report to Moderator Report to Moderator

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Sa Bon Nim
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the damage to your liver is considerable, compared to others


''Just follow the book, don't look for magic fixes to get you off the hook. Do the work.'' Dr.D.'98
DNA mt/Haplo H; Y-chrom/J2(M172);ISTJ
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Andrea AWsec
Monday, August 24, 2009, 11:36am Report to Moderator Report to Moderator

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Kyosha Nim
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Yes slow acetylator  are sensitive to caffeine. If they drink a cup late it will keep them awake.


MIFHI

"Do not try to satisfy your vanity by teaching a great many things. Awaken people's curiosity. It is enough to open minds; do not overload them." Anatole France

"Healthy people have the least overt symptoms from eating avoid foods." Dr. D'Adamo
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Andrea AWsec
Monday, August 24, 2009, 11:56am Report to Moderator Report to Moderator

SWAMI INFJ Warrior Taster
Kyosha Nim
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MIFHI

"Do not try to satisfy your vanity by teaching a great many things. Awaken people's curiosity. It is enough to open minds; do not overload them." Anatole France

"Healthy people have the least overt symptoms from eating avoid foods." Dr. D'Adamo
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nowishow
Monday, August 24, 2009, 4:43pm Report to Moderator Report to Moderator

B+ 51% Swami Explorer - D'Adamo diet since 1999
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Quoted from Magess
I wanted to send Dr. D a question, but I can't figure out how, so I thought I'd just ask the board.

How do you determine if you're a slow acetylator? I have high caffeine sensitivity, so I thought I could be one. Is that an accurate assumption?

And 2) what does being slow acetylator mean for alcohol consumption? Do they get drunker faster? Or stay drunk longer?


I'm an Explorer so I have a slow acetylator. I have a big problem with caffeine and most drugs (codeine seems to be ok) and even herbal remedies. But, I wouldn't say I get drunk faster or stay drunk longer. Of course I'm a B nonnie and on the BTD red and white wine is listed as benificial and liquor distilled as neutral. Type O or A may have a very different response.


"Anxiety is the gap between now and then"

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Chloe
Monday, August 24, 2009, 8:27pm Report to Moderator Report to Moderator

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Does being a slow or fast acetylator belong to any specific genotype or can anyone of any
genotype be fast or slow?


"The happiest people don't have the best of everything.....they know how to make the best of everything!"
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Gale D.
Monday, August 24, 2009, 8:35pm Report to Moderator Report to Moderator

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I would think anyone could because I am Teacher and have reactions to very small amounts of drugs. I can feel a single sip, and can get drunk-ish on half a glass of wine, although I don't drink.

On the other hand, I sometimes have to take drugs differently than prescribed.

One drug I'm on is usually taken 2 pills twice a day. I have to take 1 pill four times a day or I get burning liver pain.

Another drug I'm on is usually taken 800 mg twice a day. I have to take it 400 mg 4 times a day, and even at that dose, which is considered high, I can have breakthrough symptoms within a few hours if I miss a dose.




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C_Sharp
Monday, August 24, 2009, 8:51pm Report to Moderator Report to Moderator

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Quoted from Chloe
Does being a slow or fast acetylator belong to any specific genotype or can anyone of any
genotype be fast or slow?


Any GenoType can be a fast or slow acetylator.

Warriors typically are fast acetylators.

Explorers are typically slow acetylators.


MIfHI                            I follow a SWAMI diet.
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Chloe
Monday, August 24, 2009, 9:06pm Report to Moderator Report to Moderator

42% Teacher Rh+ N1, N1b
Kyosha Nim
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Would being on the right GT improve our extremes in either direction?

Are we born fast or slow acetylators?  And is being overly fast or overly slow
indicative of our declining or dysfunctional genetics?


"The happiest people don't have the best of everything.....they know how to make the best of everything!"
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C_Sharp
Monday, August 24, 2009, 9:43pm Report to Moderator Report to Moderator

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Some things in the Explorer GenoType help deal with slow acetylation.

I am not as familiar with the warrior and how it deals with fast acetylation. I think it helps deal with some of the consequences of fast acetylation and helps prevent type 2 diabetes from developing (which fast acetylators are more likely to develop).


MIfHI                            I follow a SWAMI diet.
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Lola
Monday, August 24, 2009, 10:33pm Report to Moderator Report to Moderator

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''Just follow the book, don't look for magic fixes to get you off the hook. Do the work.'' Dr.D.'98
DNA mt/Haplo H; Y-chrom/J2(M172);ISTJ
The harder you are on yourself, the easier life will be on you!
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Symbi
Tuesday, August 25, 2009, 4:51am Report to Moderator Report to Moderator

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Fair question Magess.  Hope you don't mind if I try and answer it and add a few of my own!
  
I had a Full Blood count last year and it showed low levels of Gamma-glutamyl transpeptidase http://en.wikipedia.org/wiki/Gamma_glutamyl_transpeptidase.  The GP said it doesn't matter, if it was elevated that would be a worry.

From what I understand if it was elevated you would be highly toxic and overworking the liver and kidneys, after drinking for instance within the past few weeks it says on wikipedia.  Couldn't find any information about what a low reading means.  

At the time I was following a very antioxidant full teacher-like version of the blood type diet for type A, no drinking and no drugs, can't remember if I was having coffee, probably not much.

I am sensitive to caffeine.  Does low levels of GGT prove that I'm a slow acetylator? Isn't this GGT the enzyme that takes glutathione to the cells for antioxidation?

Since I've started taking Glucosamine Sulphate (contains glutamine) my leaky gut is healed up, and I'm so much better overall, gone from acidic to alkaline, as well as better in the joints and tendonitis.  

It talks about acetylation in the monotype for Explorer (have trouble detoxing many chemicals and drugs) at http://www.4yourtype.com/explorer.asp  

Also under the warrior monotype saying that fast acetylators turn by products of well-cooked red meat into carcinogens, which is why Warriors shouldn't eat meat.  It also says:
Quoted Text
There are several alternate versions of the NAT genes, polymorphisms that are typically called 'fast', 'medium', or 'slow' acetylators. http://www.4yourtype.com/warrior.asp


I deduce from this warriors and explorers are both mostly affected by acetylation (fast or slow) which can cause different cancers in both, diabetes in Warriors or liver problems in Explorers.  Still other genotypes could be fast, medium or slow acetylators.

Sorry another question!
I wonder if in the SWAMI it adjusts your diet, no matter what genotype you are, depending on whether you have trouble with caffeine or not (are a slow acetylator or a fast acetylator)?.


INFJ ex-Ghee Whiz, GTD Explorer Sept_09 - SWAMI Mar_10

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Lola
Tuesday, August 25, 2009, 5:02am Report to Moderator Report to Moderator

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Sa Bon Nim
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takes all your data into account and designs your diet according to you, yes.


''Just follow the book, don't look for magic fixes to get you off the hook. Do the work.'' Dr.D.'98
DNA mt/Haplo H; Y-chrom/J2(M172);ISTJ
The harder you are on yourself, the easier life will be on you!
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yaeli
Tuesday, August 25, 2009, 5:35am Report to Moderator Report to Moderator

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Ee Dan
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SWAMI even gives you the option (last item) to program your diet specifically to enhance aceylation level.


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