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MTHFR   This thread currently has 1,597 views. Print Print Thread
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lisa
Monday, February 17, 2014, 2:25pm Report to Moderator Report to Moderator

Summer: Realization, expansion.
Posts: 52
Hi does anyone know what dr d take is in the MTHFR mutation gene ? Thanks a bunch


Explorer
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jayneeo
Monday, February 17, 2014, 6:59pm Report to Moderator Report to Moderator

Rh- Gatherer
Kyosha Nim
Posts: 6,237
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Location: San Jose, CA
Age: 67
this is of interest to me also as I have been doing my own research on it due my personal issues…..
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Lola
Monday, February 17, 2014, 7:37pm Report to Moderator Report to Moderator

GT1; L (a-b-); (se); PROP-T; NN
Sa Bon Nim
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''Just follow the book, don't look for magic fixes to get you off the hook. Do the work.'' Dr.D.'98
DNA mt/Haplo H; Y-chrom/J2(M172);ISTJ
The harder you are on yourself, the easier life will be on you!
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Eric
Tuesday, February 18, 2014, 8:12pm Report to Moderator Report to Moderator

Kyosha Nim
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Age: 29
Title not what I thought it was


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Lola
Tuesday, February 18, 2014, 10:46pm Report to Moderator Report to Moderator

GT1; L (a-b-); (se); PROP-T; NN
Sa Bon Nim
Admin & Columnist
Posts: 51,114
Gender: Female
Location: ''eternal spring'' Cuernavaca - Mex.
Age: 57


''Just follow the book, don't look for magic fixes to get you off the hook. Do the work.'' Dr.D.'98
DNA mt/Haplo H; Y-chrom/J2(M172);ISTJ
The harder you are on yourself, the easier life will be on you!
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Seraffa
Wednesday, February 19, 2014, 2:08am Report to Moderator Report to Moderator

Explorer!
Ee Dan
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C_Sharp
Friday, February 21, 2014, 12:56am Report to Moderator Report to Moderator

Teacher Rh+ Lewis: a+b-, NN,Taster
Sa Bon Nim
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Quoted from lisa
Hi does anyone know what dr d take is in the MTHFR mutation gene ? Thanks a bunch


Dr. D. uses the MTHFR gene in SWAMI GenoType. When you get SWAMI done by a professional, one of the settings the practitioner makes is whether a client has an MTHFR mutation.  

Setting MTHFR to either one or two copies of the mutation changes the diet recommendations.

The consumer version of SWAMI (SWAMI Xpress) does not have an MTHFR option.



MIfHI                            I follow a SWAMI diet.
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Lola
Friday, February 21, 2014, 4:01am Report to Moderator Report to Moderator

GT1; L (a-b-); (se); PROP-T; NN
Sa Bon Nim
Admin & Columnist
Posts: 51,114
Gender: Female
Location: ''eternal spring'' Cuernavaca - Mex.
Age: 57


''Just follow the book, don't look for magic fixes to get you off the hook. Do the work.'' Dr.D.'98
DNA mt/Haplo H; Y-chrom/J2(M172);ISTJ
The harder you are on yourself, the easier life will be on you!
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misspudding
Tuesday, May 6, 2014, 4:29pm Report to Moderator Report to Moderator

Rh-, MTHFR, GT4 Explorer
Autumn: Harvest, success.
Posts: 462
Gender: Female
Location: Seattle
Age: 37
My son was just tested and is homozygous, so got a copy from both his dad and I. I would argue we're all classic explorers (all O, my son and I are O neg).

It basically means you break stuff down way slower than normal, because folate is one of the ways the liver detoxes things out of your body. Less folate, more sensitive to smaller amounts of drugs and toxins.

The other thing that stinks is it raises your inflammation if you're not eating enough folate. This can totally set off autoimmunity. In my son's case, he was just diagnosed with Crohns. I believe I'm a mild Crohns sufferer, as I've had what I can only describe as "flares" in the past, which I just assumed was celiac/gluten sensitivity.

Soooo...it's not something to mess around with. Make sure you're getting plenty of greens, and beans and brown rice, if you can handle it. And once you think you've eaten enough greens, eat more greens.  




misspudding

---

Me: Celiac type gut problems; seizure disorder; MTHFR
DH: O positive
DS: O negative; "atypical" IBD - SWAMI 44% Explorer

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misspudding
Tuesday, May 6, 2014, 4:31pm Report to Moderator Report to Moderator

Rh-, MTHFR, GT4 Explorer
Autumn: Harvest, success.
Posts: 462
Gender: Female
Location: Seattle
Age: 37
Also, avoid folic acid! It competes with folate in the body, and if you're MTHFR, you do a really awful job of converting it to the active form in the body. Stick with food, if you can, but if you need supplemental, first start with some methyl B-12 for, like, a month, and then start up some methyl folate in very small doses. It can backfire if you go too quickly. And if you have any overgrowth that is causing inflammation, it can exacerbate it, so suck down some ginger, turmeric, and fish oil at the same time!




misspudding

---

Me: Celiac type gut problems; seizure disorder; MTHFR
DH: O positive
DS: O negative; "atypical" IBD - SWAMI 44% Explorer

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jayneeo
Tuesday, May 6, 2014, 6:26pm Report to Moderator Report to Moderator

Rh- Gatherer
Kyosha Nim
Posts: 6,237
Gender: Female
Location: San Jose, CA
Age: 67
Quoted from Eric
Title not what I thought it was

HA ha ha!!

this is the new elephant in the room….I really hope Dr. D takes it on in all its complexity!!! We need a researcher like him and a brain like him to tackle the ins and outs of it.

There are so many combinations of SNPs …its so individual (that word again)….like you need all those greens but not if you have the CBS mutation and can't process sulfur….etc….

This whole business is why I have insomnia and have for years…sometimes better, sometimes worse….taking the folate keeps me awake at night if it's too much…you have to get the folate up but not too fast.

Revision History (1 edits)
jayneeo  -  Tuesday, May 6, 2014, 6:44pm
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misspudding
Tuesday, May 6, 2014, 11:41pm Report to Moderator Report to Moderator

Rh-, MTHFR, GT4 Explorer
Autumn: Harvest, success.
Posts: 462
Gender: Female
Location: Seattle
Age: 37
Ahhh, the sulfur. Bummer! I think I'm okay on that front, as I haven't noticed problems with, say, Epsom salts or salads. Very complicated, indeed!

Is it still possible to get the SNP info from 23andme if you were to do the testing now?




misspudding

---

Me: Celiac type gut problems; seizure disorder; MTHFR
DH: O positive
DS: O negative; "atypical" IBD - SWAMI 44% Explorer

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jayneeo
Wednesday, May 7, 2014, 3:25am Report to Moderator Report to Moderator

Rh- Gatherer
Kyosha Nim
Posts: 6,237
Gender: Female
Location: San Jose, CA
Age: 67
as far as I know…then you put the info thru genetic genie (google it)…free…gives much more info.

Epsom salts and salads don't bother me, but eggs, and crucferous veggies do also NAC, milk thistle, etc. I still eat eggs, but not as many…and I stay away from loads of cooked greens. The way to find out is to get sulfur strips to test urine. It's not that obvious otherwise. They say lots of meat too, but I eat plenty and it doesn't give problems.
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misspudding
Wednesday, May 7, 2014, 4:36am Report to Moderator Report to Moderator

Rh-, MTHFR, GT4 Explorer
Autumn: Harvest, success.
Posts: 462
Gender: Female
Location: Seattle
Age: 37
Good to know!




misspudding

---

Me: Celiac type gut problems; seizure disorder; MTHFR
DH: O positive
DS: O negative; "atypical" IBD - SWAMI 44% Explorer

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PCUK-Positive
Thursday, May 8, 2014, 11:39am Report to Moderator Report to Moderator

Gatherer Rh+, NN, (lewis a+ b-) [Duffy Fy(a+b+) ]
Kyosha Nim
Posts: 4,875
Gender: Male
Location: UK
Age: 53
I'm Homozygous, partner is Negative and DD is Heterozygous just to keep it simple NOT lol


Kind Regards PC. FIfHI Swami III Pro

Partner (F) is O+(Non) MN. Duffy Fy(a+b+),  Lewis (a+ b-) Gatherer.
DD ( is O+(Non)NN, Duffy Fy(a+b-) Lewis (a+b-) Gatherer
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jayneeo
Friday, May 9, 2014, 6:48pm Report to Moderator Report to Moderator

Rh- Gatherer
Kyosha Nim
Posts: 6,237
Gender: Female
Location: San Jose, CA
Age: 67
homo is pretty serious…I'm hetero and have issues….
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Dr. D
Tuesday, May 13, 2014, 12:06pm Report to Moderator Report to Moderator

Peter D'Adamo
Kwan Jhang Nim
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Location: Connecticut
Age: 58
MTHFR very significant in Teacher Genotypes, less so in others. In fact, the a polymorphisms in MTHFR may well be beneficial in Hunters as the small amount of homocysteine acts as a 'pro-oxidant' resulting in greater production of the Hunter's own internal antioxidants through a mechanism called 'hormesis'.


A whole system is a living system is a learning system.’ -Stewart Brand
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Chloe
Tuesday, May 13, 2014, 2:51pm Report to Moderator Report to Moderator

42% Teacher Rh+ N1, N1b
Kyosha Nim
Posts: 9,105
Gender: Female
Location: Northeast USA
Age: 71
wanted to share this info although I haven't read it all myself.  Just an interesting take from people
who have tried various methylation protocols. I need to educate myself.  I just found my genetic
test results done in 2003 that show ++ MTHFR gene variant. Yikes!!  Of course, these people chatting aren't aware of their genotype, but still, interesting to read their discussion.

http://forums.phoenixrising.me.....2012-revision.19050/

Something else worth noting...the relationship between magnesium and MTHFR.  I can't seem to retain
magnesium....I'm, starting to understand why!

http://gotmag.org/mg-deficiency-affects-mthfr-really/

A whole website devoted to MTHFR
http://mthfr.net/


"The happiest people don't have the best of everything.....they know how to make the best of everything!"

Revision History (3 edits)
Chloe  -  Tuesday, May 13, 2014, 8:21pm
Chloe  -  Tuesday, May 13, 2014, 8:15pm
Chloe  -  Tuesday, May 13, 2014, 4:49pm
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PCUK-Positive
Tuesday, May 13, 2014, 11:06pm Report to Moderator Report to Moderator

Gatherer Rh+, NN, (lewis a+ b-) [Duffy Fy(a+b+) ]
Kyosha Nim
Posts: 4,875
Gender: Male
Location: UK
Age: 53
Quoted from Dr. D
MTHFR very significant in Teacher Genotypes, less so in others. In fact, the a polymorphisms in MTHFR may well be beneficial in Hunters as the small amount of homocysteine acts as a 'pro-oxidant' resulting in greater production of the Hunter's own internal antioxidants through a mechanism called 'hormesis'.


Nice to know we can relax a bit as Dr D is taking ALL into account in swami Pro.

Thanks Dr D.


Kind Regards PC. FIfHI Swami III Pro

Partner (F) is O+(Non) MN. Duffy Fy(a+b+),  Lewis (a+ b-) Gatherer.
DD ( is O+(Non)NN, Duffy Fy(a+b-) Lewis (a+b-) Gatherer
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cajun
Tuesday, May 13, 2014, 11:10pm Report to Moderator Report to Moderator

Teacher/Explorer
Ee Dan
Posts: 2,452
Gender: Female
Location: Southern California
Age: 62
According to what I have read recently in 23andme, MTHFR can have something to do with Parkinsons Need to read all of their latest info.
My dad has Parkinsons and he believes his mother had it also.
I need to put my data through the genie as Jayneeo suggested.


 Ao  ISFJ   Taster   Rh+  

"God gave us the gift of life. It is up to us to give ourselves the gift of living well." Voltaire
"Whisper words of wisdom. Let it be." Sir Paul McCartney
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jayneeo
Wednesday, May 14, 2014, 8:42pm Report to Moderator Report to Moderator

Rh- Gatherer
Kyosha Nim
Posts: 6,237
Gender: Female
Location: San Jose, CA
Age: 67
yes, the results for Parkinson's and Alzheimer's will appear "locked" on 23 and me, you just click on it to see results. They don't want to frighten anyone suddenly.
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cajun
Thursday, May 15, 2014, 3:29pm Report to Moderator Report to Moderator

Teacher/Explorer
Ee Dan
Posts: 2,452
Gender: Female
Location: Southern California
Age: 62
Thanks  


 Ao  ISFJ   Taster   Rh+  

"God gave us the gift of life. It is up to us to give ourselves the gift of living well." Voltaire
"Whisper words of wisdom. Let it be." Sir Paul McCartney
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Patty H
Friday, May 16, 2014, 7:30pm Report to Moderator Report to Moderator

HUNTER L(a+b-) NMg Prop Super Taster
Ee Dan
Posts: 2,207
Gender: Female
Location: Massachusetts
Age: 56
I am hetero which helps explain my toxic levels of lead and mercury.  The problem is, at least in my case, when I tried chelation therapy it shut down ALL methylation and I had to go off the chelation protocol.  I'm not sure what I can do to detox the stuff safely . . .


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Chloe
Friday, May 16, 2014, 7:44pm Report to Moderator Report to Moderator

42% Teacher Rh+ N1, N1b
Kyosha Nim
Posts: 9,105
Gender: Female
Location: Northeast USA
Age: 71
Quoted from Patty H
I am hetero which helps explain my toxic levels of lead and mercury.  The problem is, at least in my case, when I tried chelation therapy it shut down ALL methylation and I had to go off the chelation protocol.  I'm not sure what I can do to detox the stuff safely . . .


Patty, I just found this....very interesting...I didn't do well on chelation either...I am hetero too...but
feeling less freaked out when I read this is a copying error rather than a true genetic defect.

SWAMI gives most of us many cups of green vegetables...According to this, eating greens is a great solution.

http://drlwilson.com/ARTICLES/FOLIC%20ACID%20DEFECTS.htm

Eating cilantro will detox heavy metals

http://www.naturalnews.com/027942_cilantro_heavy_metals.html

...so will pectin...Modified Citrus Pectin  http://www.econugenics.com/sho.....aZsb4CFQJeOgodjUYApQ




"The happiest people don't have the best of everything.....they know how to make the best of everything!"
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jayneeo
Saturday, May 17, 2014, 4:19am Report to Moderator Report to Moderator

Rh- Gatherer
Kyosha Nim
Posts: 6,237
Gender: Female
Location: San Jose, CA
Age: 67
I'm s'posed to take chelation also…but am hesitant….high lead and cadmium. I've heard cilantro doesn't do what we wish…but can pull toxins out of tissue only to circulate around...
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