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PATHBASE


A database of blood group correlations to common diseases



Total number of records: 145 Matching records: 1

Coronary artery disease


Description:In a study of 191 coronary artery bypass candidates, investigators paradoxically found and excess of Type O over Type A. When they examined the data more closely, they concluded that that the tendency of Type A to develop blood clots more readily ("thrombotic proneness") caused a poorer prognosis. In essence, the Type As were missing from the study because they had already died in greater numbers, leaving a disproportionate excess of Type Os among the long term survivors.
ABH non-secretors have a higher incidence of heart disease, but paradoxically with the subtypes higher incidence of alcoholism, the effects of alcohol are most protective in this group as well.
References:1. Erikssen J, Thaulow E, Stormorken H, Brendemoen O, Hellem A. ABO blood groups and coronary heart disease (CHD). A study in subjects with severe and latent CHD. Thromb Haemost 1980 Jun 18;43(2):137-140





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2015-7-30: Current Date 14:31:57 GMT: Current Time


PathType is a searchable database of blood group and disease associations, clinical correlates and citations.
By Peter D'Adamo. Copyright 2001-2015.


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