PATHBASE
A database of blood group correlations to common diseases



Total number of records: 145 Matching records: 1

Auto-immune disease, Sj÷gren's syndrome


Description:Among individuals with primary Sjogren's syndrome, Lewis blood group frequency differs from that of the general population, due mainly to an increased Lewis negative phenotype (Le (a-b-)) frequency. (1)
A major risk factor for developing Sj÷gren's is being a postmenopausal woman. It occurs less commonly in younger women, children and men of any age. Other risk factors include having: an autoimmune disease, such as lupus, vasculitis, thyroid disease or scleroderma and/or a family member with Sj÷gren's.
References:1. Manthorpe R, Staub Nielsen L, et al. Lewis blood type frequency in patients with primary Sjogren's syndrome. A prospective study including analyses for A1A2BO, Secretor, MNSs, P, Duffy, Kell, Lutheran and rhesus blood groups. Scand J Rheumatol 1985;14(2):159-62





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2014-10-23: Current Date 6:10:5 GMT: Current Time


PathType is a searchable database of blood group and disease associations, clinical correlates and citations.
By Peter D'Adamo. Copyright 2001-2011.