PATHBASE
A database of blood group correlations to common diseases



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Gallstones


Description:Research shows that gallstones are much more common in Type A, as are other liver disease.

Gallstones are pieces of hard solid matter in the gallbladder. They form when components of bile (especially cholesterol and bilirubin) come out of solution and form crystals, much as sugar precipitates as crystals when we make rock candy. In the United States, almost 80 percent of patients with gallstones have stones made of hardened cholesterol Gallstones may be as small as a grain of sand or as large as a golf ball, and the gallbladder may contain anywhere from one stone to hundreds. Sometimes the gallbladder contains only crystals and stones too small to see with the naked eye. This condition is called biliary sludge.

Type A seems more prone to gallstones over the other blood types. In one study on 321 gallstone patients and compared to 688 healthy controls, group A subjects are having somewhat higher risk to be affected with the disease than those of groups B or O. (1) Type A also seems to have a greater risk of cancer of the gallbladder over the other blood types. (2)
References:1. Chakravartti MR, Chakravartti R ABO bloodgroups in cholelithiasis. Ann Genet 1979;22(3):171-2

2.Villalobos JJ, et al [A 10-year prolective study on cancer of the digestive system]. Rev Gastroenterol Mex. 1990 Jan-Mar;55(1):17-24. Spanish.





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2014-9-23: Current Date 0:45:42 GMT: Current Time


PathType is a searchable database of blood group and disease associations, clinical correlates and citations.
By Peter D'Adamo. Copyright 2001-2011.