PATHBASE
A database of blood group correlations to common diseases



Total number of records: 145 Matching records: 1

Cancer, Glioma (brain tumor)


Description:The efficacy of postoperative chemo- and immunochemotherapy was analysed according to the survival period from study of the catamnesis of patients who underwent operation for malignant (III-IV degree malignancy) gliomas. In analysing the efficacy of various schedules of combined treatment, the authors took into consideration the patients AB0 blood group because it is known that many antineoplastic antibiotics contain structures which are marked by cross reaction with the ABH isoantigens. The results of the study showed that the use of polychemotherapy and levamisole in neuro-oncological patients with A(II) and AB(IV) blood groups is promising. Levamisole and the antineoplastic antibiotic reumycin proved to be authentically effective in patients with A(II) blood group and ineffective in those with 0(I) blood group. The data obtained are recommended for use in individual selection of the schedule of chemo- and immunochemotherapy in patients with different AB0 blood group.(1)

The ABO blood group of the oligodendroglioma patient was of prognostic value. In particular, patients with blood group A had a distinctly poorer prognosis than patients with O or B blood. The survival data from this unselected series indicate that cerebral oligodendrogliomas have a less favorable prognosis than has generally been believed. (2)

The distribution of ABO blood groups was analysed statistically in 271 patients treated for glioblastoma multiforme. The control group included 500 patients treated for craniocerebral trauma. A statistically significant difference was observed in the distribution of ABO blood groups between these patient groups, with higher frequency of group A and lower of group O in the patients with glioblastoma multiforme. (3)
References:1. Zh Vopr Neirokhir Im N N Burdenko 1989 Jan-Feb;(1):17-20 [Efficacy of chemotherapy and immunochemotherapy in neuro-oncologic patients of various blood groups (ABO system)].Romodanov SA, Gnedkova IA, Lisianyi NI, Glavatskii AI.

2. Mork SJ, Lindegaard KF, Halvorsen TB, Lehmann EH, Solgaard T, Hatlevoll R, Harvei S, Ganz J. Oligodendroglioma: incidence and biological behavior in a defined population. J Neurosurg. 1985 Dec;63(6):881-9.

3. Turowski K, Czochra M. [ABO blood groups in glioblastoma multiforme]. Neurol Neurochir Pol. 1979 Mar-Apr;13(2):173-6.





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2014-4-17: Current Date 1:34:0 GMT: Current Time


PathType is a searchable database of blood group and disease associations, clinical correlates and citations.
By Peter D'Adamo. Copyright 2001-2011.