I've long thought of using the measurement of breath hydrogen levels as a way of gauging digestive and detoxification improvements in those individuals following the BTD. Last week, I bit the bullet and went ahead and purchased a unit.

Carbohydrate in the intestines can be fermented by bacteria in the small intestine, forming hydrogen as one of the by-products. Some of this hydrogen is absorbed into the blood stream and there is a direct relationship between the hydrogen concentration in expired breath and the amount of unabsorbed carbohydrate in the intestine.

The Hindenberg was full of hydrogen gas.

Each test takes about two hours, since you need several readings. The readings are then sent over to a computer program, which inventories the results.

When I get all the kinks worked out, I'll set up some sort of research study (should be easy to double blind and control it: Randomized assignments. A's who get the Standard American Diet (SAD); A's who get the A diet, etc.

‘Unabsorbed carbohydrates from the small intestine are rapidly broken down in the large intestine by colonic bacteria. This degradation liberates hydrogen, which passes into the circulation by diffusion and is then exhaled. The main source of endogenous carbohydrate secreted into the colon is mucus, an intestinal glycoprotein that is 80% carbohydrate.' –Pizzorno and Murray Textbook of Natural Medicine

Probably looking at doing the study sometime in the late fall. If you are in the Metro NYC Tri-state area and want to participate, there will be an announcement posted on the website.

Brutally cold in the NE USA. Always seems to happen at about this time, when you've just about had enough of indoor heating, early darkness, greys and browns. However, spring is going to have to arrive eventually. I'm hoping to get out on the Sound more this spring and sail. Anything to get away from the computer.

A morning spent trolling through the medical literature. In subsequent blogs, I'll add a few about each type. Some interesting findings, predominantly about type O:

People who are Type O appear less likely to kill themselves, but more likely to want to kill you:

Pub Med Link

Probably because they get a bit more depressed:

Pub Med Link

Considering the lack of any results from supplementing post menopausal women with calcium, which in the Women's Health Initiative Studies was shown to be of no benefit, perhaps those researchers should have looked at ABO blood type, since there appear to be almost three-fold differences in the rate of osteoporosis:

Pub Med Link

If you are type O, you'll want to take those headphones off:

Pub Med Link

If you are type O, your predilection for inflammation may play a role in obesity:

Pub Med Link

1.

An associate of mine, an amateur skeptic with professional zeal, says that without telling me he was acting on my recommendation to look into the Eat Right 4 Your Blood Type books, found that Dr. D'Adamo denies wheat to all four blood types in his recommendations, a little feature I hadn't picked up on. "Therefore, he's just another quack, and can be disregarded." While even if the 4-type denial is true, which I haven't checked out for myself yet, having just had this conversation, I feel a little more sympathy for it, being someone with celiac sprue. My associate, however, won't admit he has psoriasis! He said if I used that word again in talking with him, he would never communicate with me again. I was hoping to edge him toward some empirical improvement with the blood type diet, but that was ended by the hammer-fall of his judgment, at least for the present. -Peter

Hi Peter,

I'd have your friend check the book again. His calculations are off.

If we look at whole wheat

Total incidence of type A secretors = 34.2%
Total incidence of type AB secretors = 1.7%

Total percentage of the population in which whole wheat is at least 'neutral' is 36%

If we look at spelt wheat

To find the total percentage of the population in which spelt wheat is a least 'neutral' (an avoid only for type O non-secretors; about 8% of the population) is even easier. Spelt has a higher mucopolysaccharide and lower gluten content that whole wheat, which may help modulate its pro-inflammatory proteins a bit, I think.

Subtracting that serotype leaves about 92% of the population (perhaps; there are other possible reasons against) who can use spelt type wheat.

However, these numbers may be optimistic: evidence suggests that our sensitivity to gluten containing foods is on the rise.

I think we will see many possible correlations between the diseases of industrialized society (such as diabetes and obesity) and their current wheat and corn based diets.

2.

I have happened across a book I think will be of interest to you. Have never seen a reference to this on the message board. It's called 'Eat to Live', by Joel Fuhrman M.D. The book is on diet and weight loss but has a 7 page piece - critique of the BTD. At least this guy did a bit of research. -Thanks Bruce.

Hi Bruce,

Maybe you should bring it up on the Forums and see what kind of discussion ensues.

I've don't know Dr. Fuhrman and have not come across his name in any of the research areas of biology and genetics that I study. I'd like to see him stick to his own projects rather than find the time to inveigle his readers with tales and criticisms of his competitors.

There was a wonderful TV program on Isaac Newton the other night. It seemed (at least to me) that every time Newton announced a new discovery --the polychromatic nature of light, the reflecting telescope, Calculus-- this other guy (whose name I forgot) would write a critique simultaneously claiming that Newton was wrong and he that had discovered this earlier anyway. Newton apparently got seriously bent out of shape by these types of shenanigans.

Stephen Jay Gould had an interesting take on this, as part of a response to criticisms of his theory of 'Punctuated Equilibrium' (1):

THE MOST UNKINDEST CUT OF ALL. If none of the foregoing charges can bear scrutiny, strategists of personal denigration still hold an old and conventional tactic in reserve: they can proclaim a despised theory both trivial and devoid of content. This charge is so distasteful to any intellectual that one might wonder why detractors don't try such a tactic more often, and right up front at the outset. But I think we can identify a solution: the "triviality caper" tends to backfire and to hoist a critic with his own petard—for if the idea you hate is so trivial, then why bother to refute it with such intensity? Leave the idea strictly alone and it will surely go away all by itself. Why fulminate against tongue piercing, goldfish swallowing, skateboarding, or any other transient fad with no possible staying power?

Gerhard Uhlenbruck, one of our IfHI speakers, says it differently:

Never chase a lie. Let it alone, and it will run itself to death.(2)

I have my own aphorism to add:

Negative reviews of popular diet books are too often found inside of other popular diet books.

I'm actually flattered that someone would go to the trouble of writing a seven page refutation of my theory. However, I don't have the time or energy to write a seven page reponse, so this must do.

But finally, I leave you with the words of my Tang Soo Do Sa Bom:

You want to show me something you've read? Great. Get out there on the floor and show me.

(1) Stephen Gould 'The Structure of Evolutionary Thinking' (2002) Belknap, Harvard Unveristy Press.

(2) Gerhard Uhlenbruck on The Individualist.

This past Saturday (March 11th) I gave my presentation at the Institute for Integrated Nutrition. They base their weekend seminars out of the Time Warner Building in New York City, at the Jazz Theatre. What a wonderful facility! Although there were about 1,100 students in attendance, the theatre made it appear very intimate, as the audience sections went ‘up' more then ‘out' so I could almost touch, see and feel this warm, welcoming community.

I was quite worried about the timing of the lecture; I had about 2 hours, and the slides and handouts were clocked to the minute. Yet, despite my neurosis, things went off without a hitch and indeed, it ended exactly on the dime. As part of my arrangement with IIN, I've had to moderate a private online community for their students, who have been uniformly bright and respectful; a testimony to the developers of this program. So the last few days have had a definite lightness to my being; these high stakes lectures (such as the IfHI conferences) always tend to produce a quaking heaviness in the week or so before their delivery date. After everything, this heaviness lifts as in the words of Winston Churchill, I sleep ‘the sleep of the saved.'

Thanks to Joshua for the kind introduction, and Rose and Kimberly for taking such good care of me. I greatly enjoyed my visit.

Earlier this week we had performance anxieties of a different nature, as my youngest daughter Emily prepared for her performance as Joseph in the lead role in the Montessori presentation of "Joseph and the Amazing Technicolor Dream Coat.�

As any parent can attest, come performance time nerves begin to sizzle; you just so want your kid to be happy, and to do a good job of things. And if as a parent I do say so, she sang like a lark. Who knew the kid had such a beautiful voice? Joseph was a bit of an emotional stretch for her, since her four closest friends were all narrators, and got to dress up in princess-like gowns and wear makeup, whereas she had to dress rather plainly.

However, her eventual sartorial splendor brought perhaps the biggest grin I have ever seen on a human face.

More performances appear to beckon. One of the platelet disorder societies wants to set up some sort of lecture opportunity. Apparently they've had numerous individuals with bleeding disorders report back to them that the Blood Type Diets appear to influence their condition for the better. I'd like to do the lecture, but there seem to be a plethora of these obligations in the next two month, which may make doing anything else difficult if not impossible.

Interesting casual mention of the BTD on ‘Good Morning America', apparently in the context of another story on genetic testing and diet.

Oh well, practice beckons. Gotta hit the shower.

"Hi there. The study by Michael Dansinger of Tufts-New England Medical Centre in Boston may be of interest to you, if you haven't already heard about it: "One diet won't work for everyone, scientists warn slimmers" (Guardian, UK) They tested Atkins, Ornish, Zone and WeightWatchers. Why not Blood Group??? Best regards, Aidan"

The Dansinger study is interesting. For the study, he chose 160 overweight people and randomly assigned 40 to each of four different diets. They weighed an average 100kg and needed to lose between 13 and 35kg. All agreed to follow the diets to the best of their ability for two months, although none was enrolled in the full programmes that Weight Watchers and Dr Dean Ornish advocate. These include exercise, group meetings and food diaries for Weight Watchers and stress reduction for the Ornish diet. After two months, 22 per cent of the dieters had given up. After a year, 35 per cent had dropped out of Weight Watchers and the Zone diets and 50 per cent quit the Atkins and Ornish plans.

The study suggests there is no one-size-fits-all diet best for everyone. Wonder where I hear that one?

"The best way might be to be open minded about all of the options rather than focusing on finding the same 'best one' for everybody says Dansinger."

Hmm.

I think they were probably looking for diets that could go head-to-head with each other, and the BTD really can't be used for that. I remember a while back Wired magazine compared popular diets, and when they profiled the BTD, they used the type O diet and avoided mentioning the A, B and AB diets altogether.

From Wikipedia, the free encyclopedia:

Cool is a complex aesthetic of motion and interval, of tension and tranquility, of juxtaposition and coexistence, that has its roots in various West African cultures. Over time, it has been transformed by African-Americans and appropriated by American and Western popular culture, generally.

A new study seems to indicate that Tai Chi may reduce falls in the elderly. The researchers concluded that ‘Improved functional balance through Tai Chi training is associated with subsequent reductions in fall frequency in older persons,' the authors write. ‘Healthcare providers and clinicians contemplating fall-prevention programs for older persons at risk of falling should consider Tai Chi, both as a balance-retraining program, and as part of a multifaceted treatment intervention for fall prevention.'On of the main topics at ifHI 2003 was the link between elevated levels of a 'soluable endothelial factor' called E-Selectin, and individuals who are blood type A. In a nutshell E-selectin is one of several molecules that are involved in the adhesion of certain white blood cells to the artery wall, typically as a result of inflammation. Higher levels of E-selectin may contribute to the overall greater levels of heart disease seen in type A individuals.

New research indicates (again) that a 'western' level of red meat consumption results in increased levels of E-selectin. Also worth noting is that the artery inflammation caused by E-selectin is greatly enhanced by elevated levels of other blood clotting factors (Factor VIII, von Willebrand Factor) which can be up to 25% lower in normal, healthy, type O individuals when compared to type A.

E-selectin levels drop with a vegetable based diet. so if you're type A an think you need to do Atkins or Paleo, think again. You may well wind up cooking your arteries.