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STUDY: DHEA supplementation decreased the number of flare-ups and reduced disease severity
JOURNAL: Arthritis and Rheumatism (2002;46:2924–7)
ABSTRACT: Supplementing with dehydroepiandrosterone (DHEA) is beneficial for women with systemic lupus erythematosus (lupus), according to a report in Arthritis and Rheumatism (2002;46:2924–7)
COMMENTARY: The results indicate that DHEA supplementation decreased the number of flare-ups and reduced disease severity in women with active lupus.
DHEA is a steroid hormone manufactured in the adrenal glands, ovaries, and testes. Blood levels of DHEA are low in many people with lupus, and some scientists believe that DHEA deficiency may be a contributing factor to the development of the disease. DHEA modulates the activity of the immune system, which tends to be overly aggressive in individuals with lupus.