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Nonnarcotic analgesic use and the risk of hypertension
STUDY: Stay away from NSAIDS on a regular basis
JOURNAL: Hypertension 2002;40:604-8.
AUTHORS: Dedier J, Stampfer MJ, Hankinson SE
ABSTRACT: ASA, acetaminophen and ibuprofen are the most commonly used medications among adults, according to a national survey of US households.
Short-term prospective studies suggest that NSAIDs can cause acute elevations of blood pressure, and ASA and acetaminophen can influence prostaglandin homeostasis.
COMMENTARY: Short-term prospective studies suggest that NSAIDs can cause acute elevations of blood pressure, and ASA and acetaminophen can influence prostaglandin homeostasis.
The Nova Scotia Heart Health study has shown that 21% of women aged 35–64 years have hypertension, thus, even small elevations in blood pressure caused by nonnarcotic analgesic use could result in cardiovascular morbidity and mortality.